{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T04:46:41Z","timestamp":1782362801725,"version":"3.54.5"},"reference-count":30,"publisher":"S. Karger AG","issue":"12","license":[{"start":{"date-parts":[[2024,7,10]],"date-time":"2024-07-10T00:00:00Z","timestamp":1720569600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2024,7,10]],"date-time":"2024-07-10T00:00:00Z","timestamp":1720569600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int Arch Allergy Immunol"],"abstract":"<jats:p>Introduction: Urticaria is a condition that is characterized by the development of wheals (hives), angioedema, or both. If symptoms persist for less than 6 weeks, it is classified as acute urticaria (AU), and if they persist for longer than 6 weeks, it is classified as chronic urticaria (CU). Disease activity is evaluated using validated patient-reported outcome measures (PROMs) such as the 7-day urticaria activity score (UAS-7) and urticaria control test (UCT). In this study, we aimed to determine whether there was a difference between patients with chronic and recovered urticaria in terms of age, sex, symptoms, disease severity, disease control, and triggering factors by following patients with AU for 6 months. Methods: The routine tests were requested at the first admission of the patients. If previously examined, anti-thyroid peroxidase (anti-TPO), anti-nuclear antibody, etc., were recorded. After the first examination, the patients were evaluated again using a visual analog scale (VAS), UCT, UAS-7, and medication scores (MSs) in the 1st, 3rd, and 6th months. Results: One hundred nine (F\/M: 80\/29) patients were included in the study. Twenty-seven patients had a previous history of AU, 22 of these patients were evaluated as having recurrent AU, and five became chronic during follow-up. Urticaria continued in 22 of 82 patients who presented with first-attack AU in the 3rd month and 17 in the 6th month. We had a chronicity rate of 24.7%. It was determined that having positive anti-TPO increased the risk of CU 1.69 times. A statistically significant improvement was found in the mean VAS, UCT, UAS-7, and MSs evaluated in the 1st, 3rd, and 6th months of patients with CU compared with baseline. Conclusion: AU is a common disease and usually heals in a short time without becoming chronic. Studies on the causes of chronicity are limited. Testing anti-TPO in patients presenting with AU may be useful in terms of disease course and risk of chronicity. <\/jats:p>","DOI":"10.1159\/000538903","type":"journal-article","created":{"date-parts":[[2024,7,22]],"date-time":"2024-07-22T21:15:29Z","timestamp":1721682929000},"page":"1216-1225","source":"Crossref","is-referenced-by-count":2,"title":["Acute Urticaria: Symptoms, Causes, and Evaluation of Phenotypes Prone to Chronicity"],"prefix":"10.1159","volume":"185","author":[{"given":"Begum","family":"Gorgulu Akin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1505-4293","authenticated-orcid":false,"given":"Sengul","family":"Beyaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zeynep","family":"Celebi Sozener","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2024,7,10]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1111\/all.15090"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.waojou.2021.100533"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1007\/s40521-023-00333-w"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.aller.2012.05.007"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.2500\/aap.2016.37.3971"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.aller.2018.12.010"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-022-00389-z"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.anai.2013.12.005"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacig.2023.100159"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.4103\/0378-6323.45100"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.iac.2013.07.010"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.mpmed.2021.03.008"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.15586\/aei.v50iSP2.784"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3038.2010.01093.x"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.paed.2020.04.001"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1981.tb15306.x"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/s0196-0644(95)70002-1"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2016.09.029"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.4168\/aair.2017.9.3.212"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.23822\/EurAnnACI.1764-1489.12"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.2174\/1871528111312010002"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1111\/all.13182"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.5021\/ad.2016.28.2.199"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1016\/j.waojou.2020.100101"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1007\/s40618-022-01761-2"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2019.07.021"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1111\/all.14547"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1684\/ejd.2019.3674"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.720746"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2021.793409"}],"container-title":["International Archives of Allergy and Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/iaa\/article-pdf\/185\/12\/1216\/4310696\/000538903.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/iaa\/article-pdf\/185\/12\/1216\/4310696\/000538903.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T15:16:56Z","timestamp":1745421416000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000538903"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,10]]},"references-count":30,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2024,12,9]]},"published-print":{"date-parts":[[2024,12,11]]}},"URL":"https:\/\/doi.org\/10.1159\/000538903","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.25930222","asserted-by":"subject"}]},"ISSN":["1018-2438","1423-0097"],"issn-type":[{"value":"1018-2438","type":"print"},{"value":"1423-0097","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7,10]]}}}