{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T17:22:15Z","timestamp":1788888135790,"version":"build-2803163510"},"reference-count":16,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Breast Care"],"published-print":{"date-parts":[[2024]]},"abstract":"<b><i>Background:<\/i><\/b> Breast cancer is among the most prevalent malignancies in women worldwide, with substantial morbidity and mortality. Upper limb lymphedema (ULL) is a common complication after breast cancer surgery that affects patients\u2019 daily activities and quality of life. Decongestive lymphatic therapy (DLT) and intermittent pneumatic compression (IPC) therapy are 2 primary treatment methods for ULL. <b><i>Objectives:<\/i><\/b> This study aimed to compare the efficacy of DLT with IPC versus DLT alone in the management of ULL following breast cancer surgery. <b><i>Method:<\/i><\/b> PubMed Central, SCOPUS, EMBASE, MEDLINE, Cochrane Trial Registry, Google Scholar, and <ext-link ext-link-type=\"uri\" xlink:href=\"http:\/\/Clinicaltrials.gov\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\">Clinicaltrials.gov<\/ext-link> databases were comprehensively searched for randomized controlled trials (RCTs) comparing DLT with IPC and DLT alone in patients with breast cancer-related ULL. The risk of bias was evaluated using the RoB 2 tool. Pooled effect sizes were calculated using random-effects models. <b><i>Results:<\/i><\/b> A total of 1,894 citations were identified by the systematic search. Of them, 9 RCTs were included in the analysis. The pooled standardized mean difference (SMD) for percentage volume reduction was 0.63 (95% confidence interval [CI]: \u22120.24 to 1.50; <i>I<\/i><sup>2<\/sup> = 90.9%), showing no significant difference between the DLT alone and DLT combined with IPC (<i>p<\/i> = 0.15). Pain and heaviness scores were also comparable between the groups. However, there was a significant difference in external rotation joint mobility (SMD = 0.62; 95% CI: 0.08\u20131.16; <i>I<\/i><sup>2<\/sup> = 23.8%), favoring DLT with IPC. <b><i>Conclusions:<\/i><\/b> Our findings suggest that DLT with IPC and DLT alone showed similar findings in managing ULL after breast cancer surgery, with DLT with IPC showing a greater impact on external rotation joint mobility. Healthcare providers should consider patient preferences and individual factors when selecting the most appropriate treatment modality for ULL management.<\/jats:p>","DOI":"10.1159\/000538940","type":"journal-article","created":{"date-parts":[[2024,4,22]],"date-time":"2024-04-22T17:00:30Z","timestamp":1713805230000},"page":"155-164","source":"Crossref","is-referenced-by-count":12,"title":["Comparison of Intermittent Pneumatic Compression Pump as Adjunct to Decongestive Lymphatic Therapy against Decongestive Therapy Alone for Upper Limb Lymphedema after Breast Cancer Surgery: A Systematic Review and Meta-Analysis"],"prefix":"10.1159","volume":"19","author":[{"given":"Min","family":"Yao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Puchao","family":"Peng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiufang","family":"Ding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qinfang","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lijie","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2024,4,22]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers13174287"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1111\/jmwh.13012"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.5306\/wjco.v5.i3.241"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1089\/lrb.2013.0004"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.21037\/gs.2020.03.14"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD003475.pub2"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1089\/lrb.2012.0002"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n71"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.l4898"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.10976"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.21608\/ejhm.2021.189943"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1007\/s12282-013-0481-3"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1177\/0269215519888792"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.2458\/lymph.4629"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1159\/000360786"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7819-11-15"}],"container-title":["Breast Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/brc\/article-pdf\/19\/3\/155\/4243095\/000538940.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/brc\/article-pdf\/19\/3\/155\/4243095\/000538940.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T11:17:18Z","timestamp":1745407038000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000538940"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024]]},"references-count":16,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2024,6,17]]},"published-print":{"date-parts":[[2024,6,24]]}},"URL":"https:\/\/doi.org\/10.1159\/000538940","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.25657893","asserted-by":"subject"}]},"ISSN":["1661-3791","1661-3805"],"issn-type":[{"value":"1661-3791","type":"print"},{"value":"1661-3805","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024]]}}}