{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:23:51Z","timestamp":1745468631342,"version":"3.40.4"},"reference-count":5,"publisher":"S. Karger AG","issue":"5","license":[{"start":{"date-parts":[[2024,5,23]],"date-time":"2024-05-23T00:00:00Z","timestamp":1716422400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,5,23]],"date-time":"2024-05-23T00:00:00Z","timestamp":1716422400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Skin Appendage Disord"],"abstract":"<jats:p>Introduction: Onychocryptosis is a common and often painful nail condition, but risk factors have been relatively unexplored. We aimed to analyze associations between onychocryptosis, comorbidities, and income level. Methods: Using the National Institute of Health All of Us Research Program Database, a matched case-control study was performed for patients with onychocryptosis diagnosis and comorbidities and lifestyle factors. Results: A total of 6,246 cases of onychocryptosis and 24,984 controls were analyzed. Patients with onychocryptosis versus controls had increased risk of onychogryphosis (OR 5.66; 95% CI 4.87, 6.58), onychomycosis (2.63; 2.06, 3.36), hallux valgus (1.68; 1.50, 1.87), type 2 diabetes mellitus (1.49; 1.40, 1.60), obesity (1.38; 1.30, 1.48), and peripheral vascular disease (1.24; 1.14, 1.35) compared to controls. Patients who reported living in low-income households more often had onychocryptosis (reference group annual income &amp;gt;200 k; annual income &amp;lt;10 k USD, OR: 1.76; 95% CI: 1.46, 2.12, p &amp;lt; 0.001 vs. annual income 150\u2013200 k USD, OR: 1.26; 95% CI: 0.99, 1.61, p = 0.06). Conclusion: Low income, obesity, PVD, and T2DM were associated with onychocryptosis diagnosis. It is recommended that these at-risk populations be screened for onychocryptosis and counseled on proper nail trimming techniques. Future studies are needed to examine the relationship between household income and onychocryptosis risk. <\/jats:p>","DOI":"10.1159\/000538969","type":"journal-article","created":{"date-parts":[[2024,5,23]],"date-time":"2024-05-23T21:00:30Z","timestamp":1716498030000},"page":"421-424","source":"Crossref","is-referenced-by-count":0,"title":["Onychocryptosis Is Associated with Low Income in a Matched Cohort Study Using the All of Us Database"],"prefix":"10.1159","volume":"10","author":[{"given":"Rachel C.","family":"Hill","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Onajia","family":"Stubblefield","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tracey C.","family":"Vlahovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shari R.","family":"Lipner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2024,5,23]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.5070\/d3259045583"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.7547\/17-023"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpm.2004.05.009"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.38807.594792.AE"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1159\/000530096"}],"container-title":["Skin Appendage Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/sad\/article-pdf\/10\/5\/421\/4287616\/000538969.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/sad\/article-pdf\/10\/5\/421\/4287616\/000538969.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T15:17:33Z","timestamp":1745421453000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000538969"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,23]]},"references-count":5,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2024,10,8]]},"published-print":{"date-parts":[[2024,10,9]]}},"URL":"https:\/\/doi.org\/10.1159\/000538969","archive":["Portico"],"relation":{},"ISSN":["2296-9195","2296-9160"],"issn-type":[{"type":"print","value":"2296-9195"},{"type":"electronic","value":"2296-9160"}],"subject":[],"published":{"date-parts":[[2024,5,23]]}}}