{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,26]],"date-time":"2025-05-26T13:29:03Z","timestamp":1748266143488,"version":"3.40.4"},"reference-count":15,"publisher":"S. Karger AG","issue":"6","license":[{"start":{"date-parts":[[2024,6,13]],"date-time":"2024-06-13T00:00:00Z","timestamp":1718236800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2024,6,13]],"date-time":"2024-06-13T00:00:00Z","timestamp":1718236800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Skin Appendage Disord"],"abstract":"<jats:p>Introduction: Metabolic syndrome is a forerunner for adverse cardiovascular events. Its association with nail psoriasis has not been much explored. We conducted a cross-sectional study to investigate metabolic syndrome in patients with nail psoriasis as compared to psoriasis patients without nail involvement and healthy controls. Materials and Methods: Thirty each adult participants with nail psoriasis (group-I), psoriasis without nail involvement (group-II) and healthy controls (group-III) were recruited. All participants were assessed for metabolic syndrome as per National Cholesterol Education Program-Adult Treatment Plan-III (NCEP-ATP-III) criteria. Disease severity assessment and serological assessment of high-sensitivity C-reactive protein (hsCRP) level was done. Results: Higher prevalence of metabolic syndrome was found in group-I compared to group-III (33.33 vs. 20%, p = 0.420) with equal prevalence in group-I and group-II. Significantly higher prevalence of hypertension was seen in group-I and group-II (p = 0.036) as compared to group-III. Mean serum hsCRP was significantly higher for group-I as compared to group-II (p = 0.027) and group-III (p = 0.001). Weak positive correlation was seen between hsCRP levels and PASI and NAPSI scores. Conclusions: Frequency of metabolic syndrome is similar in nail psoriasis patients and psoriasis patients without nail involvement. However, higher hsCRP levels with nail psoriasis may reflect increased risk of cardiovascular comorbidities. A baseline screening with correction of modifiable risk factors should be aimed at in patients with nail psoriasis. <\/jats:p>","DOI":"10.1159\/000539150","type":"journal-article","created":{"date-parts":[[2024,7,22]],"date-time":"2024-07-22T05:46:41Z","timestamp":1721627201000},"page":"512-519","source":"Crossref","is-referenced-by-count":1,"title":["Association of Nail Psoriasis with Metabolic Syndrome: A Cross-Sectional Study"],"prefix":"10.1159","volume":"10","author":[{"given":"Anil Kumar","family":"Bhoi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chander","family":"Grover","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9201-3391","authenticated-orcid":false,"given":"Archana","family":"Singal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bineeta","family":"Kashyap","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Dibyashree","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2024,6,13]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1002\/art.21972"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1242\/dmm.001180"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.18044"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.4103\/0378-6323.72462"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.4103\/0019-5154.87144"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.4103\/0019-5154.100474"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.4103\/0019-5154.113958"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.4103\/2229-5178.131080"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.7860\/jcdr\/2016\/17791.7218"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.7860\/JCDR\/2017\/24717.9376"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.18611"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2007.07986.x"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.0000052939.59093.45"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1111\/1346-8138.12632"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.2011.04131.x"}],"container-title":["Skin Appendage Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/sad\/article-pdf\/10\/6\/512\/4311033\/000539150.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/sad\/article-pdf\/10\/6\/512\/4311033\/000539150.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T15:19:21Z","timestamp":1745421561000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000539150"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,13]]},"references-count":15,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2024,12,9]]},"published-print":{"date-parts":[[2024,12,11]]}},"URL":"https:\/\/doi.org\/10.1159\/000539150","archive":["Portico"],"relation":{},"ISSN":["2296-9195","2296-9160"],"issn-type":[{"type":"print","value":"2296-9195"},{"type":"electronic","value":"2296-9160"}],"subject":[],"published":{"date-parts":[[2024,6,13]]}}}