{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T03:06:28Z","timestamp":1791428788911,"version":"4.3.3"},"reference-count":65,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Inflamm Intest Dis"],"published-print":{"date-parts":[[2024]]},"abstract":"<jats:p>Introduction: With the recent increase in number of drugs for treating inflammatory bowel disease (IBD), it has become important to select treatments acceptable to patients. Endoscopy and biomarkers from blood and stool samples are used to evaluate IBD disease activity. This study aimed to clarify the acceptability of usage of advanced therapy and examination methods in patients through an internet-based survey. Methods: Patients with inflammatory bowel disease were asked via the internet to participate in a survey on the acceptability of nine therapies and three examination methods. The respondents rated acceptability on a scale of 1\u201310 and specified the most preferred option. Results: Responses were obtained from 388 patients with ulcerative colitis and 82 with Crohn\u2019s disease; 14.5% and 11.5% of the patients underwent intravenous infusions and subcutaneous injections, respectively. Once-daily oral administration had the highest acceptability score, which was significantly different from other administration usages (p &lt; 0.0001), regardless of prior treatment history. Oral administration was preferred by 88.9% of patients. The ranking of examination methods from most to least acceptable was blood tests &gt; endoscopy &gt; stool tests, with significant differences among all groups (p &lt; 0.0001). Blood testing (76%) and stool testing (4.5%) were the most and least preferred methods, respectively. Conclusions: The most acceptable usage of advanced therapy in patients with inflammatory bowel disease was once-daily oral administration. Treatments that are effective, safe, and acceptable to patients should be selected, and examination methods acceptable to patients should be used. <\/jats:p>","DOI":"10.1159\/000539738","type":"journal-article","created":{"date-parts":[[2024,8,27]],"date-time":"2024-08-27T08:25:56Z","timestamp":1724747156000},"page":"174-183","source":"Crossref","is-referenced-by-count":5,"title":["Patients\u2019 Preference on Advanced Therapy and Follow-Up Procedure for Inflammatory Bowel Disease in Japan: A Web-Based 3A Survey"],"prefix":"10.1159","volume":"9","author":[{"given":"Toshifumi","family":"Morishita","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shunichi","family":"Yanai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yosuke","family":"Toya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takayuki","family":"Matsumoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2024,7,17]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2011.01.055"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1007\/s00535-019-01603-8"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjv052"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjab178"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjz180"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.14309\/ajg.0000000000000152"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2018.27"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2011-300988"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2012-302830"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2020.12.031"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2015.66"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2019.07.054"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1002\/ibd.22936"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjw132"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1007\/s00535-021-01793-0"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1159\/000517339"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1093\/crocol\/otaa030"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa050516"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2011.10.032"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2013.05.048"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1900750"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1215734"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1606910"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)00666-8"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1007\/s00535-009-0057-3"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(21)00065-0"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(21)00377-0"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2021-326390"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(21)00312-5"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1905725"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(22)00688-2"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1007\/s12325-009-0069-7"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.2147\/PPA.S31115"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1007\/s12325-011-0048-7"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1002\/ibd.21164"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1002\/ibd.21491"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1080\/17474124.2021.1898944"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.1093\/ibd\/izac119"},{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.5217\/ir.2021.00143"},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjac122"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.14309\/ajg.0000000000001979"},{"key":"ref42","doi-asserted-by":"publisher","DOI":"10.1093\/ibd\/izac063"},{"key":"ref43","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2109927"},{"key":"ref44","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2018.11.035"},{"key":"ref45","doi-asserted-by":"publisher","DOI":"10.1093\/ibd\/izaa199"},{"key":"ref46","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2021-221051"},{"key":"ref47","doi-asserted-by":"publisher","DOI":"10.1007\/s12325-022-02168-4"},{"key":"ref48","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2016.01.015"},{"key":"ref49","doi-asserted-by":"publisher","DOI":"10.1111\/apt.13475"},{"key":"ref50","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)32641-7"},{"key":"ref51","doi-asserted-by":"publisher","DOI":"10.1097\/MIB.0000000000001173"},{"key":"ref52","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2015.120"},{"key":"ref53","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjx088"},{"key":"ref54","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2021.06.036"},{"key":"ref55","doi-asserted-by":"publisher","DOI":"10.1093\/ibd\/izac076"},{"key":"ref56","doi-asserted-by":"publisher","DOI":"10.1111\/jgh.15907"},{"key":"ref57","doi-asserted-by":"publisher","DOI":"10.1097\/MIB.0000000000000062"},{"key":"ref58","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-95761-6"},{"key":"ref59","doi-asserted-by":"publisher","DOI":"10.1111\/jgh.15782"},{"key":"ref60","doi-asserted-by":"publisher","DOI":"10.1111\/imj.15298"},{"key":"ref61","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2013.04.007"},{"key":"ref62","doi-asserted-by":"publisher","DOI":"10.1038\/s41395-018-0233-2"},{"key":"ref63","doi-asserted-by":"publisher","DOI":"10.1097\/MIB.0000000000000313"},{"key":"ref64","doi-asserted-by":"publisher","DOI":"10.1097\/01.MIB.0000441348.32570.34"},{"key":"ref65","doi-asserted-by":"publisher","DOI":"10.1016\/j.crohns.2013.09.012"}],"container-title":["Inflammatory Intestinal Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/iid\/article-pdf\/9\/1\/174\/4257294\/000539738.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/iid\/article-pdf\/9\/1\/174\/4257294\/000539738.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T15:25:07Z","timestamp":1745421907000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000539738"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024]]},"references-count":65,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,6,14]]}},"URL":"https:\/\/doi.org\/10.1159\/000539738","archive":["Portico"],"relation":{},"ISSN":["2296-9403","2296-9365"],"issn-type":[{"value":"2296-9403","type":"print"},{"value":"2296-9365","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024]]}}}