{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:24:21Z","timestamp":1745468661965,"version":"3.40.4"},"reference-count":10,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2024,6,27]],"date-time":"2024-06-27T00:00:00Z","timestamp":1719446400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2024,6,27]],"date-time":"2024-06-27T00:00:00Z","timestamp":1719446400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatology"],"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Introduction:&lt;\/i&gt;&lt;\/b&gt; Actinic keratoses (AKs) are rough, scaly patches from UV exposure, increasing the risk of non-melanoma skin cancer (NMSC). This study examines AK incidence in Korea and its role as a risk factor for NMSC. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; A retrospective nationwide register-based cohort study analyzed 2,917 AK patients and 14,585 controls from 2002 to 2019. Patients diagnosed with AK were followed until NMSC occurrence, death, emigration, or December 2019. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; AK incidence reached 44.8 per 100,000 person-years in 2019. The adjusted hazard ratio for NMSC in AK patients was 8.91 (95% confidence interval, 5.72\u201313.90). Higher NMSC risk was observed in female AK patients, those under 60 years, and those with lower income levels. The 16-year cumulative incidence of NMSC was 4.19% in AK patients versus 0.44% in controls. &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; AK significantly increases the risk of NMSC in Koreans, highlighting the need for tailored surveillance and treatment strategies. <\/jats:p>","DOI":"10.1159\/000539878","type":"journal-article","created":{"date-parts":[[2024,7,22]],"date-time":"2024-07-22T21:15:29Z","timestamp":1721682929000},"page":"1-5","source":"Crossref","is-referenced-by-count":0,"title":["High Risk of Non-Melanoma Skin Cancer in Actinic Keratosis Patients with Skin of Color: A Nationwide Register-Based Cohort Study"],"prefix":"10.1159","author":[{"given":"Hyoung Soo","family":"Park","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Du Jin","family":"Baek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"You Chan","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jee Woong","family":"Choi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2024,6,27]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.14852"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2005.31009"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-3486"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2023.4266"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/0895-4356(92)90133-8"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1093\/bjd\/ljad371"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0215(20010120)95:1%3c7::aid-ijc1001%3e3.0.co;2-x"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijge.2016.05.003"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-2854"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2021.02.082"}],"container-title":["Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/drm\/article-pdf\/doi\/10.1159\/000539878\/4258322\/000539878.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/drm\/article-pdf\/doi\/10.1159\/000539878\/4258322\/000539878.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T15:26:24Z","timestamp":1745421984000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000539878"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,27]]},"references-count":10,"URL":"https:\/\/doi.org\/10.1159\/000539878","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.26104669","asserted-by":"subject"}]},"ISSN":["1018-8665","1421-9832"],"issn-type":[{"type":"print","value":"1018-8665"},{"type":"electronic","value":"1421-9832"}],"subject":[],"published":{"date-parts":[[2024,6,27]]}}}