{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T17:22:55Z","timestamp":1793726575744,"version":"4.6.1"},"reference-count":45,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2024,8,29]],"date-time":"2024-08-29T00:00:00Z","timestamp":1724889600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,8,29]],"date-time":"2024-08-29T00:00:00Z","timestamp":1724889600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Skin Appendage Disord"],"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Introduction:&lt;\/i&gt;&lt;\/b&gt; Onychomycosis is a complex nail disease that is commonly seen in daily practice. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; Electronic health records of clinically diagnosed onychomycosis patients were extracted using DataDerm \u2013 a dermatology data registry hosted by the American Academy of Dermatology \u2013 spanning from the year 2016 to 2022. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; Regardless of age, an increasing trend in patient volume was observed in the Southern US region, which accounted for 50.7\u201356.9% of onychomycosis patients in 2022. A coinfection of tinea pedis was present among 15.6\u201322.5% of patients. Diagnostic testing was infrequently utilized with less than one-quarter of patients having a histopathologic examination (12.7\u201321.9%) followed by fungal culture (5.5\u20138.2%) and direct microscopic examination (3.3\u20136.0%). Treatments were infrequently prescribed, accounting for less than one-quarter of patients (orals, terbinafine: 20.8\u201329.1%, fluconazole: 12.9\u201316.5%; topicals, efinaconazole: 3.2\u201313.8%); over 30% of treated patients received a combination regimen or experienced switching of treatments. Prescribing patterns did not significantly differ in vulnerable patient groups such as elderly patients and in patients with concomitant tinea pedis. Patients receiving a topical and\/or oral antifungal prescription were frequently not tested to confirm the onychomycosis diagnosis (76.9%). &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; Our findings add to a growing body of literature calling for the improvement of onychomycosis management practices. <\/jats:p>","DOI":"10.1159\/000540704","type":"journal-article","created":{"date-parts":[[2024,8,29]],"date-time":"2024-08-29T21:03:15Z","timestamp":1724965395000},"page":"1-9","source":"Crossref","is-referenced-by-count":2,"title":["Patient Characteristics, Diagnostic Testing Utilization, and Antifungal Prescribing Pattern for Onychomycosis in the USA: A Cohort Study Using DataDerm, 2016\u20132022"],"prefix":"10.1159","author":[{"given":"Aditya K.","family":"Gupta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anh N.","family":"Tran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2024,8,29]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.149.s65.4.x"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1111\/myc.13725"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.16394"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2019.02.025"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2024.0400"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2022.06.1201"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1994.tb06087.x"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2005.06838.x"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.149.s65.5.x"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1111\/myc.13683"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2023.03.045"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1002\/hsr2.1694"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.36849\/JDD.6770"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1007\/s00403-022-02413-4"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.3390\/jof9010033"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.3390\/jof9010019"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2019.12.019"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.3399\/BJGPO.2022.0186"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1111\/ddg.14988"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.36849\/JDD.6291"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.13358"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.3390\/jof10020149"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.25259\/IJDVL_91_2022"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.23736\/S2784-8671.23.07694-6"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.3390\/jof8080831"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.3390\/jof8020135"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1111\/myc.13549"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.5070\/D327654050"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1038\/s41579-023-00960-9"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1186\/1751-0759-8-15"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.3390\/jof8010060"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1007\/s11046-016-0040-5"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-4362.1998.00550.x"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2005.01282.x"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2017.07.050"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2018.3114"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2022.1470"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.1080\/14740338.2023.2280137"},{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2023.08.086"},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.1111\/myc.13708"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.1016\/j.jid.2023.04.032"},{"key":"ref42","doi-asserted-by":"publisher","DOI":"10.3390\/jof9070710"},{"key":"ref43","doi-asserted-by":"publisher","DOI":"10.1017\/ash.2021.201"},{"key":"ref44","doi-asserted-by":"publisher","DOI":"10.1111\/myc.13660"},{"key":"ref45","doi-asserted-by":"publisher","DOI":"10.3390\/jof8050464"}],"container-title":["Skin Appendage Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/sad\/article-pdf\/doi\/10.1159\/000540704\/4272481\/000540704.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/sad\/article-pdf\/doi\/10.1159\/000540704\/4272481\/000540704.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T15:34:14Z","timestamp":1745422454000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000540704"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,29]]},"references-count":45,"URL":"https:\/\/doi.org\/10.1159\/000540704","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.26485168","asserted-by":"subject"}]},"ISSN":["2296-9195","2296-9160"],"issn-type":[{"value":"2296-9195","type":"print"},{"value":"2296-9160","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,8,29]]}}}