{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T17:41:22Z","timestamp":1780508482660,"version":"3.54.1"},"reference-count":9,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2024,9,23]],"date-time":"2024-09-23T00:00:00Z","timestamp":1727049600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2024,9,23]],"date-time":"2024-09-23T00:00:00Z","timestamp":1727049600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Rep Oncol"],"abstract":"<jats:p>Introduction: Multiple myeloma represents a malignant disorder of plasma cells. Extramedullary relapse in multiple myeloma is a rare occurrence, and pericardial involvement stands as an exceedingly uncommon manifestation. Only a few documented cases of pericardial effusion as an extramedullary relapse presentation of myeloma exist. Bispecific antibodies are emerging as a novel class of immunotherapy drugs for the treatment of relapsed refractory multiple myeloma patients who have experienced failure with four prior lines of therapy. According to a literature review, none of the reported cases with pericardial effusion relapsed myeloma have been treated with bispecific antibodies, given that these drugs have only recently gained approval. Case Presentation: We present a rare case of a patient with pericardial effusion resulting from myeloma relapse, treated with teclistamab, a bispecific antibody, and achieving an excellent response. Conclusion: Bispecific antibodies, such as teclistamab, show great effectiveness as a treatment for patients with relapsed refractory multiple myeloma, including those with extramedullary disease. <\/jats:p>","DOI":"10.1159\/000540979","type":"journal-article","created":{"date-parts":[[2024,9,23]],"date-time":"2024-09-23T16:00:33Z","timestamp":1727107233000},"page":"1063-1069","source":"Crossref","is-referenced-by-count":4,"title":["Teclistamab as an Effective Treatment for Pericardial Effusion in Relapsed Multiple Myeloma: Case Report and a Brief Literature Review"],"prefix":"10.1159","volume":"17","author":[{"given":"Sai Samyuktha","family":"Bandaru","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naveen Singh","family":"Multani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William Thomas","family":"Nauam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cibar","family":"Benitez-Ferina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2024,9,23]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1007\/s12325-011-0079-0"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.carpath.2019.02.002"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2203478"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1080\/10428190400011583"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.carpath.2019.02.002"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2018-11-884221"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2019-233340"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1007\/s40265-022-01793-1"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1038\/s41375-024-02154-5"}],"container-title":["Case Reports in Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/cro\/article-pdf\/17\/1\/1063\/4280947\/000540979.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/cro\/article-pdf\/17\/1\/1063\/4280947\/000540979.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T15:36:37Z","timestamp":1745422597000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000540979"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,23]]},"references-count":9,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,6,18]]}},"URL":"https:\/\/doi.org\/10.1159\/000540979","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.26780206","asserted-by":"subject"}]},"ISSN":["1662-6575"],"issn-type":[{"value":"1662-6575","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,23]]}}}