{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:24:58Z","timestamp":1745468698817,"version":"3.40.4"},"reference-count":16,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2024,10,8]],"date-time":"2024-10-08T00:00:00Z","timestamp":1728345600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2024,10,8]],"date-time":"2024-10-08T00:00:00Z","timestamp":1728345600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Rep Dermatol"],"abstract":"<jats:p>Introduction: Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a potentially life-threatening, drug-induced adverse reaction characterized by skin eruptions, lymphadenopathy, fever, and a broad range of other bodily manifestations. The spectrum of histopathologic and clinical presentations is wide; therefore, DRESS syndrome can mimic other diseases. Case Presentation: We present a case of a 4-year-old male patient who started chemotherapy with vincristine, cytarabine, and etoposide. The first clinical signs were fever, hemodynamic in-stability, and maculopapular erythema. Biopsies of skin lesions were taken, and hyperkeratosis, focal parakeratosis, acanthosis with slight spongiosis, and intraepithelial dyskeratotic cells were observed. There was a perivascular lymphoid infiltrate with abundant eosinophils in the dermis, and eosinophil permeations to the acrosyringium and epithelium were found. Conclusion: DRESS syndrome is a drug-induced reaction that shares histopathological findings in skin biopsies with those seen in graft-versus-host disease. Although the histological findings are non-pathognomonic, they were characteristic enough to be of importance in the differential diagnosis. <\/jats:p>","DOI":"10.1159\/000541046","type":"journal-article","created":{"date-parts":[[2024,10,8]],"date-time":"2024-10-08T16:04:55Z","timestamp":1728403495000},"page":"221-225","source":"Crossref","is-referenced-by-count":0,"title":["DRESS Syndrome That Resembles Graft-Versus-Host Disease after Chemotherapy in a Pediatric Patient: A Case Report"],"prefix":"10.1159","volume":"16","author":[{"given":"Marian","family":"Rol\u00f3n","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mateo","family":"Barros","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clara","family":"Ortiz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sergio Danilo","family":"Cruz Romero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johanna","family":"\u00c1lvarez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2024,10,8]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1080\/21548331.2018.1451205"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2018.3556"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2020.03.081"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1111\/pde.14044"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/7863815"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1592\/phco.31.3.332"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.alit.2019.03.006"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.13212"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0000000000000439"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.13683"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.4103\/0378-6323.168934"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1097\/PEC.0000000000000489"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1111\/his.13157"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.23750\/abm.v90i3-S.8159"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.5826\/dpc.0101a09"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms11020346"}],"container-title":["Case Reports in Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/cde\/article-pdf\/16\/1\/221\/4287168\/000541046.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/cde\/article-pdf\/16\/1\/221\/4287168\/000541046.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T15:37:10Z","timestamp":1745422630000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000541046"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,8]]},"references-count":16,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,6,17]]}},"URL":"https:\/\/doi.org\/10.1159\/000541046","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.26984461","asserted-by":"subject"}]},"ISSN":["1662-6567"],"issn-type":[{"type":"electronic","value":"1662-6567"}],"subject":[],"published":{"date-parts":[[2024,10,8]]}}}