{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T22:00:15Z","timestamp":1773180015085,"version":"3.50.1"},"reference-count":24,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2024,11,21]],"date-time":"2024-11-21T00:00:00Z","timestamp":1732147200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2024,11,21]],"date-time":"2024-11-21T00:00:00Z","timestamp":1732147200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Rep Ophthalmol"],"abstract":"<jats:p>Introduction: In this report, we describe the case of peripheral hypertrophic subepithelial corneal degeneration (PHSCD), managed with surgical excision and a human amniotic membrane (hAM) graft. Case Presentation: A 45-year-old female Caucasian patient presented with decreased vision, itching, and burning in both eyes, and a presence of pseudopterygium in the right eye, causing visual decline. Routine ocular exams and anterior segment OCT led to the diagnosis of PHSCD, after a careful differential diagnosis with other similar clinical occurrences. Subsequently, the patient was successfully managed with surgical intervention and an amniotic membrane graft placement. Conclusion: PHSCD is a rare disease, which in advanced cases can be successfully managed with hAM graft. No recurrence of the lesions was observed at 1-year follow-up in our patient. <\/jats:p>","DOI":"10.1159\/000541162","type":"journal-article","created":{"date-parts":[[2024,11,21]],"date-time":"2024-11-21T17:00:39Z","timestamp":1732208439000},"page":"865-872","source":"Crossref","is-referenced-by-count":1,"title":["Human Amniotic Membrane Graft in the Management of Peripheral Hypertrophic Subepithelial Corneal Degeneration: A Case Report"],"prefix":"10.1159","volume":"15","author":[{"given":"Pietro","family":"Rosetta","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruno","family":"Battaglia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sakshi","family":"Watarkar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandro","family":"Feo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2024,11,21]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1097\/01.icl.0000087489.61955.82"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2012.10.037"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1097\/01.icl.0000182875.61214.cf"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.126.9.1226"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1111\/aos.13800"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1111\/aos.12394"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2020.108351"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1038\/s41433-020-0786-3"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics12081843"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.survophthal.2018.09.004"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1097\/IIO.0b013e3181e246e5"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2022.836009"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1111\/aos.12029"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtos.2021.11.009"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0000000000002716"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1097\/01.icu.0000172827.31985.3a"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1097\/00055735-200108000-00006"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1097\/01.ico.0000151501.80952.c5"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1007\/s10561-017-9618-5"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0000000000002151"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1016\/s0002-9394(14)70125-4"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1007\/s10792-022-02570-5"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4835(83)90015-5"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.1977.tb01658.x"}],"container-title":["Case Reports in Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/cop\/article-pdf\/15\/1\/865\/4313179\/000541162.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/cop\/article-pdf\/15\/1\/865\/4313179\/000541162.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T15:38:45Z","timestamp":1745422725000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000541162"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,21]]},"references-count":24,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,6,20]]}},"URL":"https:\/\/doi.org\/10.1159\/000541162","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.27861819","asserted-by":"subject"}]},"ISSN":["1663-2699"],"issn-type":[{"value":"1663-2699","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,21]]}}}