{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T02:06:15Z","timestamp":1792202775424,"version":"4.4.0"},"reference-count":24,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2024,9,12]],"date-time":"2024-09-12T00:00:00Z","timestamp":1726099200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2024,9,12]],"date-time":"2024-09-12T00:00:00Z","timestamp":1726099200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Caries Res"],"abstract":"<jats:p>Introduction: This in situ study investigated the protective effect of a solution containing statherin-derived peptide (StatpSpS) against enamel intrinsic erosion (ERO). Methods: Fifteen volunteers wore appliances containing 2 bovine specimens. The samples were subjected to ERO with HCl, mimicking dental ERO by intrinsic acid. The volunteers participated in 3 phases (double-blind and crossover): (1) deionized water (negative control); (2) commercial solution containing SnCl&lt;sub&gt;2&lt;\/sub&gt;\/NaF\/AmF (800 ppm Sn+2, 500 ppm F\u2212, pH 4.5) (positive control); (3) solution containing 1.88 \u00d7 10\u22125&lt;sc&gt;m&lt;\/sc&gt; StatpSpS. Four times a day, the volunteers administered one drop of the solutions (50 \u03bcL, 1 min) on each specimen. After the treatment, erosive challenges were performed extraorally with 0.01 &lt;sc&gt;m&lt;\/sc&gt; HCl (pH 2.0, 4 times\/day, 1 min, 150 mL). Enamel wear was assessed by profilometry. Data were analyzed by one-way RM-ANOVA\/Bonferroni\u2019s tests (p &lt; 0.05). Results: In terms of the treatments, both the commercial solution (SnCl&lt;sub&gt;2&lt;\/sub&gt;\/NaF\/AmF) and StatpSpS significantly reduced the wear when compared to the negative control (p &lt; 0.01), without significant differences between them (p &gt; 0.05). Conclusion: The solution containing StatpSpS demonstrated protection against enamel intrinsic erosive wear. This study marks a significant advancement in the prevention of intrinsic erosive wear, utilizing StatpSpS in acquired pellicle engineering procedures. <\/jats:p>","DOI":"10.1159\/000541403","type":"journal-article","created":{"date-parts":[[2024,9,12]],"date-time":"2024-09-12T16:08:05Z","timestamp":1726157285000},"page":"1-6","source":"Crossref","is-referenced-by-count":2,"title":["Statherin-Derived Peptide Protects against Intrinsic Erosive Enamel Wear in situ"],"prefix":"10.1159","author":[{"given":"Even Akemi","family":"Taira","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina Ruis","family":"Ferrari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriel","family":"Carvalho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vinicius Taioqui","family":"Pel\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Talita Mendes Oliveira","family":"Ventura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edson","family":"Crusca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reinaldo","family":"Marchetto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00edlia Afonso Rabelo","family":"Buzalaf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2024,9,12]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1159\/000503308"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1159\/000360369"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1590\/s1678-77572012000500001"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.archoralbio.2014.02.002"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.archoralbio.2009.02.009"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1159\/000486969"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/s0021-9258(18)42650-6"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1080\/07391102.1998.10508230"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0722.2011.00899.x"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.archoralbio.2020.104890"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1007\/s10989-007-9085-0"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2020.103478"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1177\/00220345211011590"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1385\/1-59259-877-3:003"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1177\/0022034517712981"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2021.103612"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmbbm.2022.105549"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2015.10.009"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2018.12.007"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1159\/000539064"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1159\/000517959"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1159\/000360555"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-010-0386-x"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2018.04.001"}],"container-title":["Caries Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/cre\/article-pdf\/doi\/10.1159\/000541403\/4290146\/000541403.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/cre\/article-pdf\/doi\/10.1159\/000541403\/4290146\/000541403.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T15:41:17Z","timestamp":1745422877000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000541403"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,12]]},"references-count":24,"URL":"https:\/\/doi.org\/10.1159\/000541403","archive":["Portico"],"relation":{},"ISSN":["0008-6568","1421-976X"],"issn-type":[{"value":"0008-6568","type":"print"},{"value":"1421-976X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,12]]}}}