{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T03:33:41Z","timestamp":1747193621416,"version":"3.40.5"},"reference-count":26,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2024,10,17]],"date-time":"2024-10-17T00:00:00Z","timestamp":1729123200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2024,10,17]],"date-time":"2024-10-17T00:00:00Z","timestamp":1729123200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Rep Nephrol Dial"],"abstract":"<jats:p>Introduction: The Seraph\u00ae 100 Microbind\u00ae Affinity Filter is a biomimetic adsorbent device that can remove pathogens from the blood. Case Presentation: Here, we report the successful use of the Seraph\u00ae 100 to treat both a SARS-CoV-2 reinfection leading to severe COVID-19 pneumonia as well as subsequent secondary lung infections including Acinetobacter baumannii, Serratia marcescens, and Pseudomonas aeruginosa multidrug-resistant bacteria. To our knowledge, this 46-year-old black male is the first patient in which four treatments with this pathogen adsorber, one for a viral and three for different bacterial infections, have been successfully used. Conclusion: The Seraph\u00ae 100 can be easily and successfully used in conjunction with standard (anti-infective) treatment. <\/jats:p>","DOI":"10.1159\/000541422","type":"journal-article","created":{"date-parts":[[2024,10,17]],"date-time":"2024-10-17T16:00:49Z","timestamp":1729180849000},"page":"171-177","source":"Crossref","is-referenced-by-count":0,"title":["Successful Repeated Use of a Pathogen Adsorbing Biomimetic Device for the Adjunct Treatment of a SARS-CoV-2 Reinfection and Subsequent Infections with Different Multiresistant Bacteria"],"prefix":"10.1159","volume":"14","author":[{"given":"Reuben","family":"Okioma","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khalida","family":"Soki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander","family":"Hay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8110-9064","authenticated-orcid":false,"given":"Jan T.","family":"Kielstein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2024,10,17]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1159\/000508647"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfab347"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1097\/CCE.0000000000000662"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1159\/000527290"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1007\/s00063-024-01153-9"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa2021436"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2118542"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(21)00177-6"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000005493"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-021-03597-3"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-020-03398-0"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1097\/CCE.0000000000000180"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1055\/s-0041-1727121"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1093\/ckj\/sfab010"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1111\/1744-9987.14137"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1097\/MCC.0000000000000755"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6948e1"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1186\/s12941-021-00454-7"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkw372"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1007\/s11356-019-06561-5"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.26355\/eurrev_202108_26549"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.2174\/1574886316666210728113905"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2020-235262"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-022-06810-1"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0269368"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-59385-w"}],"container-title":["Case Reports in Nephrology and Dialysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/cnd\/article-pdf\/14\/1\/171\/4290423\/000541422.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/cnd\/article-pdf\/14\/1\/171\/4290423\/000541422.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T15:41:27Z","timestamp":1745422887000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000541422"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,17]]},"references-count":26,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,6,14]]}},"URL":"https:\/\/doi.org\/10.1159\/000541422","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.27003244","asserted-by":"subject"}]},"ISSN":["2296-9705"],"issn-type":[{"type":"electronic","value":"2296-9705"}],"subject":[],"published":{"date-parts":[[2024,10,17]]}}}