{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T20:43:28Z","timestamp":1778791408364,"version":"3.51.4"},"reference-count":17,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2024,9,26]],"date-time":"2024-09-26T00:00:00Z","timestamp":1727308800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2024,9,26]],"date-time":"2024-09-26T00:00:00Z","timestamp":1727308800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Audiol Neurotol"],"abstract":"<jats:p>Introduction: Jugulotympanic paraganglioma (JTP) refers to paraganglioma arising from jugular bulb, which can invade surrounding structures such as the bones, blood vessels, meninges, and cranial nerves. The authors conducted a study to find surgical indications to avoid a serious cranial nerve complications by analyzing the medical records of patients who underwent surgical management for JTP. Methods: We performed a single-institution, retrospective review of patients who underwent resection of JTP from 2004 to 2022. Patients underwent either Fisch infratemporal fossa approach type A (ITFA-A) or modification of ITFA-A with partial rerouting of the facial nerve. Preoperative and postoperative lower cranial nerve (LCN) function and facial function using the House-Brackmann (H-B) grade were evaluated. Results: The study included 19 patients with a mean age of 43.1 years (standard deviation [SD], 16.1 years). The average tumor size was 28.6 mm (SD 12.6 mm). In patients with Fisch classes C1 and C2 tumors, there were 3 and 11 patients, respectively. Gross total tumor removal (GTR) was performed in all patients with classes C1 and C2. GTR was achieved in 2 out of the 5 patients with class C3 tumor. Seventeen patients underwent ITFA-A and 2 patients underwent partial rerouting. Facial function before surgery was normal in all but 3 cases. Among 16 patients with preoperative normal facial function, 13 had H-B grade I to II and 3 had H-B grade III at 1 year after surgery. Total and partial rerouting did not significantly affect facial function immediately after surgery or at the postoperative 1-year evaluation (p = 1.00). Preoperative LCN function was normal in all patients. LCN palsy lasting more than 1 year occurred in 7 patients after surgery. Patients with Fisch class C1 tumor did not develop postoperative LCN palsy. Among the patients with class C2 tumor, none of 5 patients with medial invasion depth less than 9.5 mm developed LCN palsy, whereas 5 of 6 patients (83.3%) with invasion depth of 9.5 mm or greater developed LCN palsy (p = 0.02). Conclusion: JTPs with deep medial invasion should be managed conservatively to prevent LCN palsy. <\/jats:p>","DOI":"10.1159\/000541597","type":"journal-article","created":{"date-parts":[[2024,9,26]],"date-time":"2024-09-26T16:01:32Z","timestamp":1727366492000},"page":"1-8","source":"Crossref","is-referenced-by-count":2,"title":["Clinical Features and Surgical Outcomes of Jugulotympanic Paraganglioma"],"prefix":"10.1159","author":[{"given":"Sung Min","family":"Koh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bokhyun","family":"Song","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yang-Sun","family":"Cho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2024,9,26]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1213\/00000539-199401000-00020"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.10252"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1210\/jcem.86.11.8034"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1055\/s-2008-1058145"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.3171\/2008.10.JNS08612"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1055\/s-0028-1103127"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1177\/0003489414523711"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2013.08.004"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(20000615)88:12%3c2811::aid-cncr21%3e3.0.co;2-7"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1002\/hed.21790"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1002\/lary.1993.103.s60.65"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1177\/000348948409300615"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-015-3720-8"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1054\/jocn.2000.0865"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1111\/coa.13046"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1097\/00129492-200105000-00018"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1097\/00129492-200103000-00020"}],"container-title":["Audiology and Neurotology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/aud\/article-pdf\/doi\/10.1159\/000541597\/4291595\/000541597.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/aud\/article-pdf\/doi\/10.1159\/000541597\/4291595\/000541597.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T14:51:29Z","timestamp":1745419889000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000541597"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,26]]},"references-count":17,"URL":"https:\/\/doi.org\/10.1159\/000541597","archive":["Portico"],"relation":{},"ISSN":["1420-3030","1421-9700"],"issn-type":[{"value":"1420-3030","type":"print"},{"value":"1421-9700","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,26]]}}}