{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T06:11:56Z","timestamp":1777011116839,"version":"3.51.4"},"reference-count":15,"publisher":"S. Karger AG","issue":"6","license":[{"start":{"date-parts":[[2024,11,21]],"date-time":"2024-11-21T00:00:00Z","timestamp":1732147200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2024,11,21]],"date-time":"2024-11-21T00:00:00Z","timestamp":1732147200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int Arch Allergy Immunol"],"abstract":"<jats:p>Introduction: Perioperative immediate hypersensitivity (POH) is a rare complication estimated at 1\/10,000 anaesthesia. The objective of our study was to investigate the risk factors of POH over a 6-year period in a French teaching hospital. Materials and Methods: A single-centre retrospective descriptive epidemiological study of patients treated in the operating room from January 2016 to December 2021 with and without POH. Results: 111 POH were identified out of 47,585 surgeries, mainly women (71%) with a history of asthma (16% vs. 6%, p &lt; 0.001) undergoing plastic surgery (49% vs. 32%, p &lt; 0.001). POH patients were more likely to receive neuromuscular blocking agents and antibiotics (respectively, 88% vs. 59%, p &lt; 0.001 and 59% vs. 24%, p &lt; 0.001). 92% of patients underwent intraoperative sampling, only 31% benefited from an allergy consultation. 14% had positive skin test (ST). The culprit agent were neuromuscular blocking agents (47% of which 57% rocuronium, 29% suxamethonium, and 14% atracurium), antibiotics (33%, of which 80% cefazolin and 20% cefoxitin), and gelatin (7%). Conclusion: Our study reported a POH incidence of 23\/10,000 anaesthesia, with identified allergens aligning with existing literature. These findings underscore the critical need for enhanced patient follow-up to monitor potential hypersensitivity and mitigate future risks. <\/jats:p>","DOI":"10.1159\/000542734","type":"journal-article","created":{"date-parts":[[2024,11,21]],"date-time":"2024-11-21T12:00:46Z","timestamp":1732190446000},"page":"551-555","source":"Crossref","is-referenced-by-count":2,"title":["Exploring the Landscape of Perioperative Immediate Hypersensitivity: A Comprehensive 6-Year Monocentric Observational Analysis on Epidemiology and Risk Factors"],"prefix":"10.1159","volume":"186","author":[{"given":"Arthur","family":"Moreau","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00e9nyssa","family":"Ch\u00e9rifa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric","family":"Roland","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathleen","family":"Mc Gee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beno\u00eet","family":"Plaud","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aur\u00e9lie","family":"Gouel-Cheron","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alice","family":"Blet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2024,11,21]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bja.2018.04.001"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2011.03.003"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2007.01347.x"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.annfar.2010.12.002"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1111\/all.13820"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejim.2022.03.003"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.bja.2019.01.002"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2016-012647"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.anai.2017.07.009"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.waojou.2019.100022"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1111\/all.13456"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.bja.2019.01.027"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aeq366"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.bja.2019.04.044"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.anrea.2017.09.003"}],"container-title":["International Archives of Allergy and Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/iaa\/article-pdf\/doi\/10.1159\/000542734\/4316857\/000542734.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000542734","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T16:03:54Z","timestamp":1758297834000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000542734"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,21]]},"references-count":15,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2025,6,5]]},"published-print":{"date-parts":[[2025,5,28]]}},"URL":"https:\/\/doi.org\/10.1159\/000542734","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.27861573","asserted-by":"subject"}]},"ISSN":["1018-2438","1423-0097"],"issn-type":[{"value":"1018-2438","type":"print"},{"value":"1423-0097","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,21]]}}}