{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T01:24:05Z","timestamp":1788312245453,"version":"build-2803163510"},"reference-count":20,"publisher":"S. Karger AG","issue":"5","license":[{"start":{"date-parts":[[2024,12,10]],"date-time":"2024-12-10T00:00:00Z","timestamp":1733788800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2024,12,10]],"date-time":"2024-12-10T00:00:00Z","timestamp":1733788800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Respiration"],"abstract":"<jats:p>Introduction: The incidence of pulmonary imaging abnormalities continues to increase. While standard convex probe endobronchial ultrasound bronchoscope (CP-EBUS) is safe and accurate, it has limited reach through smaller bronchi. Olympus BF-Y0069 thin convex probe EBUS (TCP-EBUS) has a smaller diameter and improved angulation. We assessed the safety and feasibility of the TCP-EBUS to evaluate lesions not accessible with CP-EBUS. Methods: A single-center, prospective, pilot study evaluating TCP-EBUS enrolled patients undergoing bronchoscopy for lesions within the inner two-thirds of the lung. Patients underwent CP-EBUS to attempt visualization and biopsy. If unsuccessful, TCP-EBUS was used. Safety, lesion characteristics, and pathology results were collected. Results: Fifty-one patients were enrolled with multiple lesion locations and no adverse safety events with TCP-EBUS. Seven cases (13.7%) were omitted as the target lesion was visualized by CP-EBUS and TCP-EBUS. CP-EBUS failed to provide biopsy for 44 cases. CP-EBUS visualized 7\/44, however, was unable to biopsy. TCP-EBUS visualized 36\/44 (81.8%) lesions and biopsied 27\/44 (61%) lesions. 8\/44 (15.7%) lesions could not be visualized with either device. Median lesion size biopsied with CP-EBUS was 41 mm (IQR: 22\u201348). Median size of lesions visualized with TCP-EBUS was 20 mm (IQR: 15.3\u201338), range 8\u201370. The median distance from the main carina was 62 mm (IQR: 60\u201389) for lesions biopsied with the CP-EBUS and 63.3 (IQR: 48.5\u201378.8) for TCP-EBUS. While average distances from main carina were similar in both groups, the furthest lesion TCP-EBUS visualized was 120 mm from the carina compared to 100 mm with CP-EBUS. Conclusions: The use of TCP-EBUS was safe and effective without observed patient-associated complications, and it provided real-time ultrasonographic visualization and biopsy of lesions not accessible with CP-EBUS. <\/jats:p>","DOI":"10.1159\/000542966","type":"journal-article","created":{"date-parts":[[2024,12,10]],"date-time":"2024-12-10T17:26:59Z","timestamp":1733851619000},"page":"332-340","source":"Crossref","is-referenced-by-count":8,"title":["First in Human Evaluation of a Novel Thin Convex Probe Endobronchial Ultrasound System"],"prefix":"10.1159","volume":"104","author":[{"given":"Nicholas J.","family":"Pastis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vidhya Y.","family":"Aroumougame","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher R.","family":"Gilbert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam H.","family":"Fox","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nichole T.","family":"Tanner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Travis L.","family":"Ferguson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerard A.","family":"Silvestri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2024,12,10]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1097\/LBR.0000000000000892"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.12-2355"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2018.08.1026"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1513\/AnnalsATS.201311-384OC"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.lungcan.2023.107196"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1111\/1759-7714.14454"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2022.12.044"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2019.12.024"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezu028"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2202170"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1097\/JTO.0000000000000453"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacr.2022.04.010"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.17925\/usrpd.2017.12.02.33"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.congress-2023.pa5215"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1159\/000357066"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201505-0990OC"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics13142393"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1055\/s-0034-1395498"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.21037\/tlcr-22-120"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1513\/AnnalsATS.201607-568BC"}],"container-title":["Respiration"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000542966","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000542966","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,2]],"date-time":"2025-05-02T16:02:00Z","timestamp":1746201720000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000542966"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,10]]},"references-count":20,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2025,5,2]]},"published-print":{"date-parts":[[2025,5,7]]}},"URL":"https:\/\/doi.org\/10.1159\/000542966","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.27990305","asserted-by":"subject"}]},"ISSN":["0025-7931","1423-0356"],"issn-type":[{"value":"0025-7931","type":"print"},{"value":"1423-0356","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12,10]]}}}