{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,21]],"date-time":"2025-06-21T04:04:23Z","timestamp":1750478663457,"version":"3.41.0"},"reference-count":25,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2025,3,21]],"date-time":"2025-03-21T00:00:00Z","timestamp":1742515200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2025,3,21]],"date-time":"2025-03-21T00:00:00Z","timestamp":1742515200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Breast Care"],"abstract":"<jats:p>&lt;p&gt;Introduction: Breast hypertrophy is the abnormal enlargement of breast tissue resulting in extremely large breasts and is a regular condition among women worldwide. It can affect different aspects of their life, including their psycho-social, sexual, emotional, and physical well-being. This study aimed to assess the quality of life in individuals with breast hypertrophy both before and after undergoing breast reduction surgery. Methods: Two sets of questionnaires (preoperative and post-operative) were formulated and distributed to 18 patients (median age of 31, age range: 18\u201348 years) undergoing breast reduction surgery. Patients were also provided with an informed consent form. Results: Preoperatively, most patients expressed different levels of dissatisfaction with themselves across all categories. However, post-operatively, significant levels (p &lt; 0.05, p &lt; 0.001) of satisfaction were demonstrated by patients, as 100% of them reported a reduction in back pain and heaviness of breasts, and 100% reported improvement in their self-confidence. Also, 94% and 65% reported improvement in their social interaction and sexual life, respectively, while 83% and 61% of patients reported satisfaction in carrying their grocery shopping bags and their engagement in regular exercise programs, respectively. Conclusion: The study illustrates that breast reduction surgery had a positive effect on the quality of life of patients as a significant proportion of them reported improvement and satisfaction across all categories following the procedure. &lt;\/p&gt;<\/jats:p>","DOI":"10.1159\/000543306","type":"journal-article","created":{"date-parts":[[2025,3,21]],"date-time":"2025-03-21T17:15:26Z","timestamp":1742577326000},"page":"170-181","source":"Crossref","is-referenced-by-count":0,"title":["Quality of Life in Patients Pre- and Post-Breast Reduction Surgery in a South African Population: A Single-Centred Patient-Based Study"],"prefix":"10.1159","volume":"20","author":[{"given":"Nokubonga","family":"Khwela","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anil","family":"Madaree","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nivana","family":"Mohan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lelika","family":"Lazarus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2025,3,21]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1053\/aq.1999.v19.100635001"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1089\/jwh.2021.0405"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-200006000-00009"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1097\/01.prs.0000246407.87267.46"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000005620"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.6061\/clinics\/2018\/e313"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e31824a2efc"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.spinee.2024.10.009"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1186\/s12891-021-04790-9"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.4103\/1117-1936.181422"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2019-031804"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1089\/jwh.2006.0183"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-200010000-00005"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1080\/02844310903258910"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1097\/SAP.0b013e31829d2261"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0186591"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0000000000007263"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e31829587b5"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2021.06.008"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1007\/s00266-009-9409-x"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1093\/asj\/sjv174"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.9063"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1016\/j.sopen.2019.10.002"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1097\/01.prs.0000152435.03538.43"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsams.2018.09.226"}],"container-title":["Breast Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000543306","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000543306","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,20]],"date-time":"2025-06-20T16:02:40Z","timestamp":1750435360000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000543306"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,21]]},"references-count":25,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2025,6,20]]},"published-print":{"date-parts":[[2025,6,24]]}},"URL":"https:\/\/doi.org\/10.1159\/000543306","archive":["Portico"],"relation":{},"ISSN":["1661-3791","1661-3805"],"issn-type":[{"type":"print","value":"1661-3791"},{"type":"electronic","value":"1661-3805"}],"subject":[],"published":{"date-parts":[[2025,3,21]]}}}