{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T09:22:58Z","timestamp":1777454578937,"version":"3.51.4"},"reference-count":12,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2025,1,8]],"date-time":"2025-01-08T00:00:00Z","timestamp":1736294400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,1,8]],"date-time":"2025-01-08T00:00:00Z","timestamp":1736294400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cerebrovasc Dis Extra"],"abstract":"<jats:p>Introduction: This case report illustrates the complexities of arrhythmogenic right ventricular cardiomyopathy (ARVC) and its thromboembolic complications resulting in top-of-basilar artery syndrome. We discuss the case of a 37-year-old male with ARVC who presented with acute onset of dizziness, imbalance, and vomiting, leading to the diagnosis of a top-of-basilar artery occlusion (BAO) which was successfully treated. Case Presentation: This case highlights the diagnostic and acute treatment challenges in BAO due to its non-specific symptoms and emphasizes the critical role of CT angiography in detecting occlusive thrombi for timely intervention. With prompt endovascular thrombectomy and bridging intravenous thrombolysis, complete recanalization was achieved and the patient was discharged with modified Rankin Scale (mRS) of 1. Effective management strategies involve assessing ventricular function, detecting arrhythmias, identifying intracardiac thrombi, and implementing individualized stroke prevention measures, such as using direct oral anticoagulants. Conclusion: This study illustrates the necessity of a multidisciplinary approach in optimizing patient outcomes in acute stroke care. Focusing on the rare condition of ARVC and the specific challenge of top-of-BAOs in this case underscores the intricate interplay between cardiovascular and cerebrovascular pathology leading to improved understanding and management of these conditions. <\/jats:p>","DOI":"10.1159\/000543418","type":"journal-article","created":{"date-parts":[[2025,1,9]],"date-time":"2025-01-09T17:00:52Z","timestamp":1736442052000},"page":"73-80","source":"Crossref","is-referenced-by-count":1,"title":["Top-of-Basilar Artery Occlusion Thromboembolism in Arrhythmogenic Right Ventricular Cardiomyopathy Treated with Intravenous Thrombolysis and Mechanical Thrombectomy"],"prefix":"10.1159","volume":"15","author":[{"given":"Amirul Asyraf Abdul","family":"Ghapar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khairul Azmi","family":"Abd Kadir","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Grace Sze Ern","family":"Chu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mei Ling Sharon","family":"Tai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamad Imran","family":"Idris","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ru Peng","family":"New","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Imran","family":"Zainal Abidin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khean Jin","family":"Goh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1177-6379","authenticated-orcid":false,"given":"Kay Sin","family":"Tan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2025,1,8]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.120.018866"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.114.004884"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1002\/ehf2.13597"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2019.05.007"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eul053"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1177\/1941874415583847"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10132750"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2206317"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.4103\/0028-3886.273639"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eul053"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2207576"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(09)70173-5"}],"container-title":["Cerebrovascular Diseases Extra"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/cee\/article-pdf\/15\/1\/73\/4320859\/000543418.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/cee\/article-pdf\/15\/1\/73\/4320859\/000543418.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T15:08:45Z","timestamp":1745420925000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000543418"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,8]]},"references-count":12,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,1,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000543418","archive":["Portico"],"relation":{},"ISSN":["1664-5456"],"issn-type":[{"value":"1664-5456","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,8]]}}}