{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,14]],"date-time":"2025-10-14T00:53:48Z","timestamp":1760403228953,"version":"build-2065373602"},"reference-count":20,"publisher":"S. Karger AG","issue":"5","license":[{"start":{"date-parts":[[2025,1,21]],"date-time":"2025-01-21T00:00:00Z","timestamp":1737417600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,1,21]],"date-time":"2025-01-21T00:00:00Z","timestamp":1737417600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["GE Port J Gastroenterol"],"abstract":"<jats:p>Introduction: Peritoneal mesothelioma (PeM) is a rare cancer of the peritoneal lining. Unlike pleural mesothelioma, PeM is less frequently linked to asbestos exposure. Chronic serosal inflammation, as seen in Crohn\u2019s disease (CD), has been proposed as a contributing factor in its carcinogenesis. Case Presentation: A male with a long-standing history of ileal CD presented with recurrent episodes of intestinal subocclusion. Imaging showed complex active ileal CD, new-onset ascites, and peritoneal densification. Intraoperatively, a small bowel mass adherent to the sigmoid colon and millimetric nodules of the peritoneum were identified. Histology of the resected segment showed CD-related changes and multiple areas of epithelioid mesothelioma, despite no asbestos exposure. He received cytoreductive surgery and hyperthermic intraperitoneal chemotherapy, with no signs of recurrence after 15 months. Discussion\/Conclusion: We present a rare case of non-asbestos-related PeM in a patient with long-standing active CD, highlighting the diagnostic challenges and possible link between chronic serosal inflammation and PeM. <\/jats:p>","DOI":"10.1159\/000543667","type":"journal-article","created":{"date-parts":[[2025,1,22]],"date-time":"2025-01-22T12:00:59Z","timestamp":1737547259000},"page":"314-319","source":"Crossref","is-referenced-by-count":0,"title":["Peritoneal Mesothelioma in a Patient with Long-Standing Crohn\u2019s Disease: Cause or Coincidence?"],"prefix":"10.1159","volume":"32","author":[{"given":"Rita","family":"Prata","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro","family":"Lages Martins","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ver\u00f3nica P.","family":"Borges","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro","family":"Botelho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ant\u00f3nio","family":"Figueiredo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5032-6127","authenticated-orcid":false,"given":"Jaime","family":"Ramos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2025,1,21]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdl345"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.21037\/tlcr.2019.12.15"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.3390\/cancers15194704"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.3390\/cells12162048"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.5858\/arpa.2017-0365-RA"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(23)02586-2"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.935275"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2017.06.051"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2020-320945"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1136\/jclinpath-2016-203945"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22084292"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.2008.058693"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.00889"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1097\/PGP.0000000000000762"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1136\/jclinpath-2018-205099"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000001574"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2020.02.011"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2023.7055"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2023.0045"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2024.7031"}],"container-title":["GE - Portuguese Journal of Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/pjg\/article-pdf\/doi\/10.1159\/000543667\/4326334\/000543667.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000543667","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T16:01:14Z","timestamp":1760371274000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000543667"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,21]]},"references-count":20,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2025,10,13]]},"published-print":{"date-parts":[[2025,10,15]]}},"URL":"https:\/\/doi.org\/10.1159\/000543667","archive":["Portico"],"relation":{},"ISSN":["2341-4545","2387-1954"],"issn-type":[{"type":"print","value":"2341-4545"},{"type":"electronic","value":"2387-1954"}],"subject":[],"published":{"date-parts":[[2025,1,21]]}}}