{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:23:41Z","timestamp":1745468621727,"version":"3.40.4"},"reference-count":26,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2025,2,3]],"date-time":"2025-02-03T00:00:00Z","timestamp":1738540800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,2,3]],"date-time":"2025-02-03T00:00:00Z","timestamp":1738540800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Rep Oncol"],"abstract":"<jats:p>Introduction: Primary breast lymphoma (PBL) is a rare non-Hodgkin lymphoma, predominantly presenting as diffuse large B-cell lymphoma (DLBCL) and primarily affecting the breast, often misdiagnosed due to its nonspecific symptoms resembling breast carcinoma. Breast implants are among the most frequently used medical devices for esthetic and reconstructive purposes. Case Presentation: We present a 24-year-old female with a growing breast mass who was diagnosed with PBL (non-Hodgkin\u2019s DLBCL). She underwent successful R-CHOP chemotherapy, resulting in complete remission. Follow-up imaging showed no distant metastasis or significant residual disease, with silicone implants intact and no pathological uptake. Conclusion: PBL is a rare malignancy that primarily affects postmenopausal women, with diagnosis relying on radiologic investigations and histopathology due to its clinical and imaging similarities to breast carcinoma. Treatment is controversial and often involves rituximab-based chemotherapy, intrathecal methotrexate, and radiotherapy, with improved outcomes observed in recent years. <\/jats:p>","DOI":"10.1159\/000543952","type":"journal-article","created":{"date-parts":[[2025,2,3]],"date-time":"2025-02-03T17:01:13Z","timestamp":1738602073000},"page":"271-277","source":"Crossref","is-referenced-by-count":0,"title":["Primary Breast Lymphoma in a Young Female: Non-Hodgkin\u2019s Diffuse Large B-Cell Lymphoma in the Presence of Intact Breast Prostheses"],"prefix":"10.1159","volume":"18","author":[{"given":"Ahmad","family":"Al-Bitar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amnah","family":"Zahreddin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammed","family":"Shwin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdullah","family":"Barbar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alaa","family":"Dirani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2025,2,3]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2020.10.029"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1111\/1754-9485.12905"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.3978\/j.issn.2304-3865.2014.12.01"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdt192"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdw175"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197206)29:6%3c1705::aid-cncr2820290640%3e3.0.co;2-i"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19901215)66:12%3c2602::aid-cncr2820661224%3e3.0.co;2-u"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1007\/s11805-011-0570-z"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1080\/08998280.2013.11928939"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.10163"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1177\/1179545x17725034"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.clml.2016.09.004"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1259\/bjr\/78413721"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-4741.2002.08509.x"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.22753"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.135.3.7384445"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7819-10-151"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2022-250478"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2013-009037"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.21353"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1016\/j.clbc.2012.07.006"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdm471"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000254418.90192.59"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.5858\/2008-132-565-EL"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.73069"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijscr.2024.110120"}],"container-title":["Case Reports in Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/cro\/article-pdf\/18\/1\/271\/4330276\/000543952.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/cro\/article-pdf\/18\/1\/271\/4330276\/000543952.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T15:14:41Z","timestamp":1745421281000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000543952"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,3]]},"references-count":26,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,1,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000543952","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.28331309","asserted-by":"subject"}]},"ISSN":["1662-6575"],"issn-type":[{"type":"electronic","value":"1662-6575"}],"subject":[],"published":{"date-parts":[[2025,2,3]]}}}