{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,30]],"date-time":"2025-05-30T06:43:36Z","timestamp":1748587416090,"version":"3.40.4"},"reference-count":10,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T00:00:00Z","timestamp":1740096000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T00:00:00Z","timestamp":1740096000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Rep Oncol"],"abstract":"<jats:p>Introduction: Spontaneous tumor lysis syndrome (TLS) is a rare, life-threatening metabolic complication that typically occurs in malignancies with high tumor burden. Early recognition is critical, even in the absence of a known malignancy, to prevent severe outcomes. Case Presentation: We report the case of an 89-year-old male with a history of chronic kidney disease, hyperparathyroidism, and myasthenia gravis, who experienced three episodes of TLS within 1 month. Initially, his metabolic disturbances were misattributed to dehydration. During his second admission, imaging revealed extensive lymphadenopathy, and a lymph node biopsy confirmed follicular helper T-cell lymphoma before his third hospitalization. Despite aggressive treatment, he developed metabolic encephalopathy and lost his decision-making capacity, while his family declined palliative care discussions. Conclusion: This case highlights the importance of considering TLS in patients with unexplained hyperkalemia, hyperuricemia, and hyperphosphatemia, even in the absence of a malignancy diagnosis. Early diagnosis and multidisciplinary care are essential to improve outcomes. <\/jats:p>","DOI":"10.1159\/000544865","type":"journal-article","created":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T17:02:00Z","timestamp":1740157320000},"page":"413-419","source":"Crossref","is-referenced-by-count":1,"title":["Recurrent Spontaneous Tumor Lysis Syndrome in Undiagnosed Follicular T-Cell Lymphoma"],"prefix":"10.1159","volume":"18","author":[{"given":"Feehaan H.","family":"Sultan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Priya K.","family":"Jindal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zeeshaan H.","family":"Sultan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nahush R.","family":"Bansal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuhao","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2025,2,21]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/9684909"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.111251"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1159\/000509643"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.htct.2023.02.005"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.11002"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1007\/s12288-013-0264-1"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2007.15.0177"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1186\/s12904-020-00566-5"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1007\/s41649-024-00321-5"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-1497.2000.07228.x"}],"container-title":["Case Reports in Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/cro\/article-pdf\/18\/1\/413\/4342321\/000544865.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/cro\/article-pdf\/18\/1\/413\/4342321\/000544865.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T15:17:53Z","timestamp":1745421473000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000544865"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,21]]},"references-count":10,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,1,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000544865","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.28451144","asserted-by":"subject"}]},"ISSN":["1662-6575"],"issn-type":[{"type":"electronic","value":"1662-6575"}],"subject":[],"published":{"date-parts":[[2025,2,21]]}}}