{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T12:32:50Z","timestamp":1793795570609,"version":"4.6.1"},"reference-count":47,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2025,4,16]],"date-time":"2025-04-16T00:00:00Z","timestamp":1744761600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,4,16]],"date-time":"2025-04-16T00:00:00Z","timestamp":1744761600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiorenal Med"],"abstract":"<jats:p>Background: An increased blood pressure variability (BPV) is associated with a high risk of cardiovascular events in the general population. This concept was scarcely tested in patients with chronic kidney disease (CKD). We investigated the behavior of BPV parameters in a large cohort of older patients with CKD. Methods: This retrospective cohort study included patients \u226575 years old with eGFR \u226460 mL\/min. Three systolic and diastolic consecutive blood pressure (BP) measurements were obtained automatically per visit (short term \u2013 3 consecutive measurements) and across visits (long term \u2013 across visits). We calculated (1) standard deviation (SD); (2) coefficient of variation (SD divided by the BP average); and (3) variability independent of the mean (VIM). For each BPV parameter, patients were divided into quartiles. Results: We included 1,063 patients (17,363 measurements). For short BPV, the higher systolic BPV (SD and VIM) was associated with older age, a lower proportion of males, and a higher proportion of patients with pulse pressure (PP) &gt;40 mm Hg. Higher diastolic BPV (SD and VIM) was associated with lower body mass index, lower eGFR, and a higher proportion of PP &gt;40 mm Hg (for SD). Bland-Altman plots revealed comparable results between short- and long-term BPV. Conclusion: A higher BPV was associated with reduced renal function in older patients with CKD. Our study also suggests that short- and long-term BPV can be used with similar results. Further studies are needed to confirm the association between BPV and outcomes and understand the physiological mechanisms underlying this correlation. <\/jats:p>","DOI":"10.1159\/000545403","type":"journal-article","created":{"date-parts":[[2025,4,16]],"date-time":"2025-04-16T16:01:32Z","timestamp":1744819292000},"page":"347-357","source":"Crossref","is-referenced-by-count":2,"title":["Blood Pressure Variability in Older Patients with Chronic Kidney Disease"],"prefix":"10.1159","volume":"15","author":[{"given":"Davi Wei Ming","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruna Cristine D.","family":"Rodrigues","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria 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