{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,8]],"date-time":"2025-05-08T04:11:36Z","timestamp":1746677496318,"version":"3.40.5"},"reference-count":15,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2025,4,4]],"date-time":"2025-04-04T00:00:00Z","timestamp":1743724800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,4,4]],"date-time":"2025-04-04T00:00:00Z","timestamp":1743724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Rep Oncol"],"abstract":"<jats:p>Introduction: Fibrillary glomerulonephritis (FGN) is a rare form of immune complex-mediated primary glomerular disease frequently coexisting with malignancies or autoimmune diseases. The kidney prognosis is extremely poor, with approximately 50% of patients progressing to end-stage kidney disease within 2\u20134 years after diagnosis. However, no established treatment currently exists. Case Presentation: Here we describe a rare case of FGN diagnosed in a patient progressing from monoclonal gammopathy to multiple myeloma. The histopathological findings of the kidney biopsy were consistent with classical FGN and revealed no evidence of myeloma cast nephropathy. Albumin-dominant, Bence Jones protein-negative proteinuria further supported this diagnosis. The patient was successfully treated with anti-myeloma chemotherapies including autologous stem cell transplant, resulting in significant improvement in kidney function. Conclusion: Based on our experience, secondary FGN associated with plasma cell neoplasms may represent a rare entity that responds favorably to anti-myeloma therapies. Initial investigations to rule out coexistent plasma cell neoplasms are crucial for the optimal management of FGN patients. <\/jats:p>","DOI":"10.1159\/000545498","type":"journal-article","created":{"date-parts":[[2025,4,5]],"date-time":"2025-04-05T16:02:48Z","timestamp":1743868968000},"page":"554-562","source":"Crossref","is-referenced-by-count":0,"title":["Fibrillary Glomerulonephritis and Multiple Myeloma: A Case Report and Literature Review"],"prefix":"10.1159","volume":"18","author":[{"given":"Taiki","family":"Ishida","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ken","family":"Morita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yosuke","family":"Masamoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideaki","family":"Mizuno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuki","family":"Taoka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Abe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Motoki","family":"Odawara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yosuke","family":"Hirakawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaomi","family":"Nangaku","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mineo","family":"Kurokawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2025,4,4]]},"reference":[{"doi-asserted-by":"publisher","key":"ref1","DOI":"10.1038\/ki.1987.66"},{"doi-asserted-by":"publisher","key":"ref2","DOI":"10.1681\/ASN.2007070757"},{"doi-asserted-by":"publisher","key":"ref3","DOI":"10.2215\/CJN.03870319"},{"doi-asserted-by":"publisher","key":"ref4","DOI":"10.1016\/j.kint.2019.03.021"},{"doi-asserted-by":"publisher","key":"ref5","DOI":"10.1681\/ASN.2017030306"},{"doi-asserted-by":"publisher","key":"ref6","DOI":"10.1681\/ASN.2017050566"},{"doi-asserted-by":"publisher","key":"ref7","DOI":"10.1053\/j.ajkd.2013.03.031"},{"doi-asserted-by":"publisher","key":"ref8","DOI":"10.1038\/ki.1992.433"},{"doi-asserted-by":"publisher","key":"ref9","DOI":"10.1093\/oxfordjournals.ndt.a027409"},{"doi-asserted-by":"publisher","key":"ref10","DOI":"10.2215\/CJN.08300910"},{"doi-asserted-by":"publisher","key":"ref11","DOI":"10.1016\/s0272-6386(12)70138-5"},{"doi-asserted-by":"publisher","key":"ref12","DOI":"10.1046\/j.1523-1755.2003.00853.x"},{"doi-asserted-by":"publisher","key":"ref13","DOI":"10.1159\/000455390"},{"doi-asserted-by":"publisher","key":"ref14","DOI":"10.1016\/j.ekir.2019.04.013"},{"doi-asserted-by":"publisher","key":"ref15","DOI":"10.1016\/j.ekir.2017.07.017"}],"container-title":["Case Reports in Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000545498","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000545498","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,7]],"date-time":"2025-05-07T16:01:46Z","timestamp":1746633706000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000545498"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,4]]},"references-count":15,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,1,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000545498","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.28731476","asserted-by":"subject"}]},"ISSN":["1662-6575"],"issn-type":[{"type":"electronic","value":"1662-6575"}],"subject":[],"published":{"date-parts":[[2025,4,4]]}}}