{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:24:10Z","timestamp":1745468650465,"version":"3.40.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2025,3,29]],"date-time":"2025-03-29T00:00:00Z","timestamp":1743206400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,3,29]],"date-time":"2025-03-29T00:00:00Z","timestamp":1743206400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["GE Port J Gastroenterol"],"abstract":"<jats:p>Introduction:\nCeliac crisis is a rare, severe manifestation of celiac disease, characterized by acute gastrointestinal symptoms, malnutrition, metabolic disturbances, and potential life-threatening complications. Postpartum celiac crisis is particularly rare but can be triggered by the physiological and hormonal changes of the puerperal period.\nCase Presentation:\nWe report the case of a 42-year-old woman with a three-month history of watery diarrhea, significant weight loss, extremity paresthesias, muscle spasms, and lower limb edema following childbirth. Initial evaluation revealed severe malnutrition, electrolyte imbalances, and hypoalbuminemia. Endoscopic studies showed significant villous atrophy and mucosal damage, suggestive of celiac disease, which was confirmed by serological and histological findings. The patient was diagnosed with celiac crisis and initiated on a strict gluten-free diet with supportive care, resulting in full clinical and biochemical recovery.\nDiscussion:\nThis case highlights the importance of considering CD in the differential diagnosis of postpartum malnutrition and chronic diarrhea. Postpartum period may trigger the disease, underscoring the need for awareness in clinical settings. Celiac hepatitis is a prevalent occurrence within the spectrum of CD, with transient transaminase elevation with resolution following the initiation of a gluten-free diet. Celiac crisis, though rare, requires prompt diagnosis and intervention to avoid further complications.\n\nIntrodu\u00e7\u00e3o:\nA crise cel\u00edaca \u00e9 uma manifesta\u00e7\u00e3o grave e rara da doen\u00e7a cel\u00edaca, caracterizada por sintomas gastrointestinais agudos, desnutri\u00e7\u00e3o, dist\u00farbios metab\u00f3licos e complica\u00e7\u00f5es potencialmente fatais. A crise cel\u00edaca no per\u00edodo p\u00f3s-parto \u00e9 rara, podendo ser desencadeada pelas altera\u00e7\u00f5es fisiol\u00f3gicas e hormonais do puerp\u00e9rio. \nApresenta\u00e7\u00e3o do Caso:\nReportamos o caso de uma mulher de 42 anos com antecedentes de diarreia aquosa, perda de peso significativa, parestesias nos membros, espasmos musculares e edema nos membros inferiores com tr\u00eas meses de evolu\u00e7\u00e3o ap\u00f3s o parto. A avalia\u00e7\u00e3o inicial revelou desnutri\u00e7\u00e3o grave, desequil\u00edbrios eletrol\u00edticos e hipoalbumin\u00e9mia. Estudos endosc\u00f3picos revelaram atrofia das vilosidades, sugestivo de doen\u00e7a cel\u00edaca, confirmado por estudos serol\u00f3gico e histol\u00f3gico. Foi feito o diagn\u00f3stico de crise cel\u00edaca e a doente iniciou uma dieta isenta de gl\u00faten e terap\u00eautica de suporte, com consequente melhoria cl\u00ednica e bioqu\u00edmica.\nDiscuss\u00e3o: \nEste caso destaca a import\u00e2ncia de considerar a doen\u00e7a cel\u00edaca no diagn\u00f3stico diferencial de desnutri\u00e7\u00e3o e diarreia cr\u00f3nica no per\u00edodo p\u00f3s-parto. As altera\u00e7\u00f5es no per\u00edodo p\u00f3s-parto podem despoletar a doen\u00e7a, refor\u00e7ando-se a necessidade de consciencializa\u00e7\u00e3o desta entidade neste contexto cl\u00ednico. A hepatite cel\u00edaca \u00e9 uma entidade prevalente no espetro da doen\u00e7a cel\u00edaca, caraterizada pelo aumento transit\u00f3rio de transaminases e com resolu\u00e7\u00e3o ap\u00f3s ado\u00e7\u00e3o de dieta isenta de gl\u00faten. A crise cel\u00edaca, embora rara, requer um diagn\u00f3stico e interven\u00e7\u00e3o atempados de modo a evitar complica\u00e7\u00f5es.\n<\/jats:p>","DOI":"10.1159\/000545520","type":"journal-article","created":{"date-parts":[[2025,3,29]],"date-time":"2025-03-29T17:10:47Z","timestamp":1743268247000},"page":"1-12","source":"Crossref","is-referenced-by-count":0,"title":["Celiac Crisis in the Postpartum: a life-threatening cause of diarrhea and malnutrition"],"prefix":"10.1159","author":[{"given":"Madalena","family":"Pestana","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N\u00e9lia","family":"Abreu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9854-086X","authenticated-orcid":false,"given":"Vitor","family":"Magno Pereira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulo","family":"C\u00e2mara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henrique","family":"Morna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2025,3,29]]},"container-title":["GE - Portuguese Journal of Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/pjg\/article-pdf\/doi\/10.1159\/000545520\/4358194\/000545520.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/pjg\/article-pdf\/doi\/10.1159\/000545520\/4358194\/000545520.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T15:23:01Z","timestamp":1745421781000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000545520"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,29]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000545520","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.28668503","asserted-by":"subject"}]},"ISSN":["2341-4545","2387-1954"],"issn-type":[{"type":"print","value":"2341-4545"},{"type":"electronic","value":"2387-1954"}],"subject":[],"published":{"date-parts":[[2025,3,29]]}}}