{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T04:20:57Z","timestamp":1770092457487,"version":"3.49.0"},"reference-count":28,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2025,4,14]],"date-time":"2025-04-14T00:00:00Z","timestamp":1744588800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,4,14]],"date-time":"2025-04-14T00:00:00Z","timestamp":1744588800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Urol Int"],"abstract":"<jats:p>&lt;p&gt;Introduction: Metastasis-directed therapy (MDT) is a promising approach for recurrent or de novo oligo-metastatic castration-sensitive prostate cancer (omCSPC). The aim of this study was to evaluate the treatment approaches in omCSPC among German physicians. Methods: An anonymous online questionnaire was sent via &lt;ext-link ext-link-type=\"uri\" xlink:href=\"http:\/\/survio.com\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\"&gt;survio.com&lt;\/ext-link&gt; to the members of the German Societies of Urology and Radiooncology. Results: Participants (n = 166; 33% urologists, 66% radiooncologists) define omCSPC as \u22643 (31%) or \u22644 (58%) metastases. Multimodal therapy consisting of local therapy of the primary tumor, MDT, and androgen deprivation therapy (ADT) was favored. For local therapy, radiotherapy was the preferred approach (radiotherapy: 84%, prostatectomy: 16%). Overall, 77% and 76% considered MDT as (very) highly important in synchronous and metachronous omCSPC, respectively. In total, 80% would complement MDT with time-limited ADT. Compared to urologists, radiooncologists more often include cases with \u22653 metastases (p = 0.006) and see a higher importance of radiotherapy (p = 0.023), a lower importance of prostatectomy (p &lt; 0.001) as well as a higher importance of MDT (in de novo p = 0.038, in metachronous p = 0.010). Conclusion: MDT with time-limited ADT is a common treatment strategy in omCSPC. Especially in synchronous omCSPC, radiotherapy as local treatment for the primary is the preferred option rather than radical prostatectomy. &lt;\/p&gt;<\/jats:p>","DOI":"10.1159\/000545630","type":"journal-article","created":{"date-parts":[[2025,4,14]],"date-time":"2025-04-14T12:01:06Z","timestamp":1744632066000},"page":"18-27","source":"Crossref","is-referenced-by-count":0,"title":["Treatment Strategies in Oligo-Metastatic Prostate Cancer: A Nationwide Survey"],"prefix":"10.1159","volume":"110","author":[{"given":"Angelika","family":"Borkowetz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernd","family":"Wullich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6351-8056","authenticated-orcid":false,"given":"Matthias","family":"Saar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nina","family":"Schmidt-Hegemann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johannes","family":"Linxweiler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2025,4,14]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.20.03488"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.22.00644"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.euo.2021.10.002"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-019-02950-0"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2022.05.031"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2019.01.049"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2021.05.016"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)32486-3"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2017.75.4853"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.20.00818"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1704174"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1007\/s00066-022-01925-2"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2023.113290"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1503747"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1111\/iju.14586"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2022.10.005"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.euf.2019.08.012"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2024.01.021"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2020.0147"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1038\/nrurol.2016.175"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.3390\/curroncol31060245"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2016.08.002"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1995.13.1.8"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-022-10374-0"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30314-7"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2016.10.044"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1016\/j.euo.2023.09.007"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2023.0161"}],"container-title":["Urologia Internationalis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/uin\/article-pdf\/doi\/10.1159\/000545630\/4365291\/000545630.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000545630","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T17:02:17Z","timestamp":1770051737000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000545630"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,14]]},"references-count":28,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,2,2]]},"published-print":{"date-parts":[[2026,2,3]]}},"URL":"https:\/\/doi.org\/10.1159\/000545630","archive":["Portico"],"relation":{},"ISSN":["0042-1138","1423-0399"],"issn-type":[{"value":"0042-1138","type":"print"},{"value":"1423-0399","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,14]]}}}