{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T20:32:41Z","timestamp":1770064361370,"version":"3.49.0"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2025,4,17]],"date-time":"2025-04-17T00:00:00Z","timestamp":1744848000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2025,4,17]],"date-time":"2025-04-17T00:00:00Z","timestamp":1744848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Skin Appendage Disord"],"abstract":"<jats:p>Background: Severity of alopecia areata (AA) has been commonly defined by clinician assessment of scalp hair loss.\n\nObjective: To characterize patient-reported factors beyond scalp hair loss that contribute to AA severity, while modifying for socioeconomic factors.\n\nMethods: Patients with AA were recruited to take a survey. Multivariable linear regression was performed to evaluate lifetime AA severity while adjusting for socioeconomic variables, current AA severity at the time of survey, and patient-reported disease burden. \n\nResults:  Patient-reported AA severity was associated with scalp hair loss (OR 4.19, 95% CI [1.35-13], p=0.013), facial hair loss (OR 3.55, 95% CI [1.75-7.21], p&lt;0.001), increased financial burden (OR 2.41, 95% CI [1.21-4.8], p=0.013), and greater emotional burden (OR 2.96, 95% CI [1.48-5.93], p=0.002), while presence of comorbidities were linked to less severe AA (OR 0.38, 95% CI [0.17-0.84], p=0.017).\n\nLimitations: Survey population was homogeneous and may not reflect the general community with AA. Self-reported data may introduce recency or recall bias. \n\nConclusion: Scalp and facial hair loss, along with emotional and financial burdens, correlate with increased patient-reported AA severity. This suggests factors beyond scalp hair loss should be considered when assessing AA severity.<\/jats:p>","DOI":"10.1159\/000545861","type":"journal-article","created":{"date-parts":[[2025,4,17]],"date-time":"2025-04-17T16:02:17Z","timestamp":1744905737000},"page":"1-9","source":"Crossref","is-referenced-by-count":1,"title":["Components of Severity in Alopecia Areata"],"prefix":"10.1159","author":[{"given":"Katherine","family":"Sanchez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ursula","family":"Biba","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samantha","family":"Gregoire","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natasha Atanaskova","family":"Mesinkovska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monique Margaret","family":"Waldman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa","family":"Anderson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arash","family":"Mostaghimi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2025,4,17]]},"container-title":["Skin Appendage Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/sad\/article-pdf\/doi\/10.1159\/000545861\/4366193\/000545861.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/sad\/article-pdf\/doi\/10.1159\/000545861\/4366193\/000545861.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T15:25:25Z","timestamp":1745421925000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000545861"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,17]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000545861","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.28796144","asserted-by":"subject"}]},"ISSN":["2296-9195","2296-9160"],"issn-type":[{"value":"2296-9195","type":"print"},{"value":"2296-9160","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,17]]}}}