{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T17:02:58Z","timestamp":1775149378780,"version":"3.50.1"},"reference-count":51,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T00:00:00Z","timestamp":1745884800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T00:00:00Z","timestamp":1745884800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuroepidemiology"],"abstract":"<jats:p>Introduction: Migraine is a widespread neurological disorder that significantly affects quality of life. However, data on its burden in China remain limited. This study analyzes long-term trends (1990\u20132021) and projects future patterns. Methods: Using the Global Burden of Disease (GBD) 2021 database, we examined migraine incidence, prevalence, and disability-adjusted life-years (DALYs). Temporal trends were assessed via joinpoint regression, while age-period-cohort (APC) analysis and decomposition analyses identified key influences. Bayesian APC modeling projected future trends through 2035. Results: Migraine imposes a substantial health burden in China, with an annual incidence of 13.04 million cases, a prevalence of 184.75 million cases, and 6.98 million DALYs cases. Females are disproportionately affected, with peak prevalence occurs in the 30\u201349 age group. Individuals born post-1960 show increased susceptibility, as linked to demographic and lifestyle shifts. Population growth is a major driver of rising prevalence, with projections indicating a continued increase through 2035. Conclusion: Migraine remains a significant public health concern in China, particularly among women. Targeted prevention, early detection, and intervention strategies are essential to mitigate its growing burden.<\/jats:p>","DOI":"10.1159\/000545886","type":"journal-article","created":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T12:02:03Z","timestamp":1745928123000},"page":"303-315","source":"Crossref","is-referenced-by-count":0,"title":["Long-Term Trends in the Burden of Migraine in China: A Comprehensive Analysis from 1990 to 2021 and Projections to 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