{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T22:42:58Z","timestamp":1785796978105,"version":"3.56.0"},"reference-count":49,"publisher":"S. Karger AG","issue":"5","license":[{"start":{"date-parts":[[2025,4,17]],"date-time":"2025-04-17T00:00:00Z","timestamp":1744848000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2025,4,17]],"date-time":"2025-04-17T00:00:00Z","timestamp":1744848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ann Nutr Metab"],"abstract":"<jats:p>Introduction: Being overweight, with a body mass index (BMI) \u226525, is associated with multiple comorbidities, including chronic kidney disease (CKD). A plant-based diet, such as a vegetarian or lacto-ovo vegetarian diet, serves as a preventive strategy for CKD in patients. We hypothesized that a vegetarian diet lowers the occurrence of CKD in overweight subjects. Methods: The retrospective study was performed in Taipei Tzu Chi Hospital by a self-paid health exam. Age younger than 40 years old and the subjects without sufficient biochemical or hematologic results were excluded. The incidence of CKD was evaluated according to the self-reported eating habits (vegetarians, lacto-ovo vegetarians, or omnivores), overweight (with a BMI \u226525 or higher abdominal circumference [&gt;90 cm in males or &gt;80 cm in females]) or not, or other biochemical or hematologic parameters. The interaction between different factors for the development of CKD was analyzed by structural equation modeling (SEM). Results: Among these 6,567 subjects, the subjects with lacto-ovo vegetarian diet had a lower incidence of CKD than those with other dietary habits such as vegans and omnivores. The incidence of overweight was the highest in the omnivore group. The lacto-ovo vegetarian group had a lower risk of CKD occurrence than the omnivore group. After adjusting for age and sex in SEM, the lacto-ovo vegetarian diet lowered the risk of CKD for those with a high BMI or a higher triglyceride (TG)\/high-density lipoprotein (HDL) ratio. Conclusion: Lacto-ovo vegetarian dietary habits are associated with a lower occurrence of CKD in obese patients. The mitigating effect of the lacto-ovo vegetarian diet was due to the hazard of a higher BMI and TG\/HDL ratio. <\/jats:p>","DOI":"10.1159\/000545953","type":"journal-article","created":{"date-parts":[[2025,4,17]],"date-time":"2025-04-17T12:02:02Z","timestamp":1744891322000},"page":"301-310","source":"Crossref","is-referenced-by-count":5,"title":["Plant-Based Diet Mitigated the Risk of Chronic Kidney Disease in Overweight 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