{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T22:31:42Z","timestamp":1787524302010,"version":"build-2736575974"},"reference-count":15,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2025,5,9]],"date-time":"2025-05-09T00:00:00Z","timestamp":1746748800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2025,5,9]],"date-time":"2025-05-09T00:00:00Z","timestamp":1746748800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Stereotact Funct Neurosurg"],"abstract":"<jats:p>Introduction: Benign adult familial myoclonus epilepsy (BAFME) is an autosomal dominant disorder characterized by adult-onset cortical tremor and infrequent generalized seizures. Treatment options for managing involuntary movements in BAFME remain limited. Case Presentation: Here, we present 2 cases involving individuals with BAFME who underwent Vim thalamotomy for tremor-like myoclonus. Despite the intervention, neither patient experienced any improvement in their symptoms. Conclusion: These findings suggest that the Vim may not contribute to the pathophysiology of tremor-like myoclonus in BAFME, despite the established efficacy of Vim thalamotomy in the treatment of essential tremor. <\/jats:p>","DOI":"10.1159\/000546301","type":"journal-article","created":{"date-parts":[[2025,5,9]],"date-time":"2025-05-09T12:01:50Z","timestamp":1746792110000},"page":"258-262","source":"Crossref","is-referenced-by-count":2,"title":["Lack of Therapeutic Benefit of Ventral Intermediate Nucleus Thalamotomy for Tremor-Like Myoclonus in Two Cases of Benign Adult Familial Myoclonus Epilepsy"],"prefix":"10.1159","volume":"103","author":[{"given":"Taku","family":"Nonaka","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Asahi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiro","family":"Horisawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ichiro","family":"Takumi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiyonobu","family":"Ikeda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akikazu","family":"Nakamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenko","family":"Azuma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Akagawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiro","family":"Yamamoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nobutaka","family":"Yamamoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takaomi","family":"Taira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2025,5,9]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1111\/epi.17519"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1515\/medgen-2021-2100"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1111\/epi.17430"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200002173420703"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1159\/000528825"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2018-318240"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.clineuro.2008.10.015"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1038\/srep41042"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-015-7748-x"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.7916\/D8NZ8DXP"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1159\/000315464"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2010.02884.x"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1684\/epd.2019.1072"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1002\/mdc3.12372"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1002\/epi4.12467"}],"container-title":["Stereotactic and Functional Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000546301","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000546301","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T16:01:24Z","timestamp":1758556884000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000546301"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,9]]},"references-count":15,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2025,9,22]]},"published-print":{"date-parts":[[2025,9,24]]}},"URL":"https:\/\/doi.org\/10.1159\/000546301","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.28982420","asserted-by":"subject"}]},"ISSN":["1011-6125","1423-0372"],"issn-type":[{"value":"1011-6125","type":"print"},{"value":"1423-0372","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,9]]}}}