{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T21:23:13Z","timestamp":1791235393049,"version":"4.1.0"},"reference-count":13,"publisher":"S. Karger AG","issue":"8","license":[{"start":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T00:00:00Z","timestamp":1750204800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T00:00:00Z","timestamp":1750204800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Blood Purif"],"abstract":"<jats:p>Introduction: Dialysis regimen and setting (home or in the center), whenever possible, should be a patient choice. While a frequent and more intensive schedule has clinical benefits, incremental or decremental dialysis is a choice in specific clinical scenarios. In Brazil, dialysis is mostly funded by the public health system and modality other than conventional 3 times a week is affordable only for patients with private health insurance. We had the opportunity to investigate the characteristics of patients triaged into a given modality\/schedule clinical in a private center. Methods: This retrospective cohort study included patients who initiated hemodiafiltration at home or in the facility between January 1, 2021, and January 1, 2024. Patients were divided into 4 groups: A (incremental\/decremental, N = 11, &lt;3 times a week or &lt;12 h\/week); B (conventional, N = 64, 3 to 4 times a week); C (short daily, N = 46, 5\u20136 times a week); and D (long nocturnal, N = 17, 6\u20138 h, 3\u20134 times a week). We evaluated the clinical and laboratory features of patients according to each group while initiating therapy and hospitalization rate. Results: Patients allocated to group D were younger and less likely to have diabetes, 94.1% had an arteriovenous fistula, and 64.7% were employed and had higher albumin and phosphate when starting the modality (p &lt; 0.05 for all comparisons). Patients on home dialysis were older, mostly on short daily dialysis, most likely to have diabetes and use a catheter, and had lower hemoglobin, albumin, and parathormone levels at the modality initiation (p &lt; 0.05 for all comparisons). Hospitalization rates did not differ among groups. Conclusion: Younger patients tended to choose a nocturnal in-center regime, whereas older patients tended to choose more frequent home dialysis. This information is critical to planning a dialysis portfolio that fits patients\u2019 needs when initiating dialysis. <\/jats:p>","DOI":"10.1159\/000546452","type":"journal-article","created":{"date-parts":[[2025,6,19]],"date-time":"2025-06-19T12:00:38Z","timestamp":1750334438000},"page":"517-523","source":"Crossref","is-referenced-by-count":2,"title":["Alternative versus Conventional Hemodialysis Regimen: One Size Does Not Fit All"],"prefix":"10.1159","volume":"54","author":[{"given":"Carolina S.","family":"Wagner","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea O.","family":"Magalh\u00e3es","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cynthia M.","family":"Borges","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sidney T.","family":"Sasaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel R.","family":"Alves","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo P.","family":"Luciano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando T.","family":"Nakagawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo M.","family":"Oliveira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Whellington F.","family":"Rocha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2212-041X","authenticated-orcid":false,"given":"Rosilene M.","family":"Elias","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2025,6,18]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa021583"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1001593"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2015.02.331"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/s1073-4449(98)70018-4"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/s0272-6386(03)00531-6"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1038\/ki.2011.213"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2023.01.006"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfg1074"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.2002.00678.x"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1038\/nrneph.2014.89"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.xkme.2019.11.006"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.nefroe.2024.07.002"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2015.09.025"}],"container-title":["Blood Purification"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000546452","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000546452","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,25]],"date-time":"2025-08-25T16:00:38Z","timestamp":1756137638000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000546452"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,18]]},"references-count":13,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2025,8,25]]},"published-print":{"date-parts":[[2025,8,27]]}},"URL":"https:\/\/doi.org\/10.1159\/000546452","archive":["Portico"],"relation":{},"ISSN":["0253-5068","1421-9735"],"issn-type":[{"value":"0253-5068","type":"print"},{"value":"1421-9735","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,18]]}}}