{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T12:50:43Z","timestamp":1765371043331,"version":"3.46.0"},"reference-count":11,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2025,7,31]],"date-time":"2025-07-31T00:00:00Z","timestamp":1753920000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,7,31]],"date-time":"2025-07-31T00:00:00Z","timestamp":1753920000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Rep Nephrol Dial"],"abstract":"<jats:p>&lt;p&gt;Introduction: Post-streptococcal acute glomerulonephritis (PSAGN) is a disease in which patients develop hematuria and leg edema following streptococcal infection, which may lead to acute nephritic syndrome and nephrotic syndrome. We present a case involving acute kidney injury and nephrotic syndrome with nonspecific pathological findings for PSAGN, which posed diagnostic challenges. Case Presentation: A 25-year-old man presented with leg edema, cough, nephrotic syndrome, severe kidney dysfunction, and hematuria. Blood tests showed elevated antistreptolysin O levels and decreased complement C3 levels; therefore, PSAGN was suspected. Light microscopy revealed membranoproliferative glomerulonephritis, immunofluorescence staining revealed a full-house pattern, and electron microscopy revealed subendothelial deposition. The diagnosis was difficult, however, positive glomerular staining for nephritis-associated plasmin receptor and plasmin activity strongly suggested an infection-related etiology of glomerulonephritis. Treatment included the administration of 500 mg of methylprednisolone for 3 days, followed by 4 weeks of treatment with 50 mg of prednisolone. Subsequently, the dosage was reduced to 40 mg, and the patient was discharged. Urinary findings revealed resolution of hematuria 1 year after discharge. Conclusion: When PSAGN is suspected and other diseases are difficult to exclude, nephritis-associated plasmin receptor staining should be considered. &lt;\/p&gt;<\/jats:p>","DOI":"10.1159\/000546484","type":"journal-article","created":{"date-parts":[[2025,7,31]],"date-time":"2025-07-31T16:01:07Z","timestamp":1753977667000},"page":"198-205","source":"Crossref","is-referenced-by-count":0,"title":["Nephritis-Associated Plasmin Receptor-Positive Post-Streptococcal Acute Glomerulonephritis Showing Full-House Pattern: A Case Report"],"prefix":"10.1159","volume":"15","author":[{"given":"Yusuke","family":"Takahashi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoto","family":"Kawata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7365-7685","authenticated-orcid":false,"given":"Hiroki","family":"Nishiwaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshinori","family":"Sato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshiharu","family":"Ueno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Oda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fumihiko","family":"Koiwa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2025,7,31]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.5527\/wjn.v11.i5.139"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22020905"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2010060611"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2004040341"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2011.04.011"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.3109\/0886022X.2010.510614"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.clim.2008.04.005"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.55.5409"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1006\/meth.2000.0990"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.5114\/ceji.2021.112244"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1159\/000500304"}],"container-title":["Case Reports in Nephrology and Dialysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000546484","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T09:11:04Z","timestamp":1765357864000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000546484"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,31]]},"references-count":11,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,1,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000546484","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.29712854","asserted-by":"subject"}]},"ISSN":["2296-9705"],"issn-type":[{"type":"electronic","value":"2296-9705"}],"subject":[],"published":{"date-parts":[[2025,7,31]]}}}