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Early recognition is hampered by variability in definitions and limited access to imaging in many regions. Summary: Comprehensive Geriatric Assessment (CGA) offers an integrated framework \u2013 spanning physical, functional, cognitive, psychological, and social domains \u2013 to improve the screening, diagnosis, and longitudinal monitoring of sarcopenia in older adults. Key Messages: (1) CGA-guided care enables tailored interventions that combine protein-rich nutrition, progressive-resistance exercise and \u2013 in selected cases \u2013 emerging pharmacological agents. (2) Economic analyses indicate CGA can be cost-neutral or cost-saving when targeted to high-risk groups, but workforce requirements challenge its scalability outside well-resourced centers. (3) Evidence remains heterogeneous and drawn largely from urban, high-income settings; caution is required when generalizing outcomes to rural or low-resource environments. (4) Future research should standardize a muscle-specific CGA core set, test implementation in diverse health systems, and evaluate digital tools that reduce staff time without widening the digital divide.<\/jats:p>","DOI":"10.1159\/000546715","type":"journal-article","created":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T16:01:23Z","timestamp":1756396883000},"page":"955-968","source":"Crossref","is-referenced-by-count":1,"title":["Application of Comprehensive Geriatric Assessment in Assessment, Management and Prognosis of Older Adult Patients with Sarcopenia: A Review of Research Progress and 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