{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T02:39:39Z","timestamp":1774924779011,"version":"3.50.1"},"reference-count":43,"publisher":"S. Karger AG","issue":"5","license":[{"start":{"date-parts":[[2025,7,10]],"date-time":"2025-07-10T00:00:00Z","timestamp":1752105600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2025,7,10]],"date-time":"2025-07-10T00:00:00Z","timestamp":1752105600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuroepidemiology"],"abstract":"<jats:p>Introduction: Dementia, particularly Alzheimer\u2019s disease (AD), represents a significant public health challenge in China, with Chongqing experiencing rapid population aging and a rising prevalence of dementia. Early prevention and public education are critical to mitigating dementia risk; however, public awareness of AD remains low, with significant knowledge gaps and misconceptions. This study aimed to assess the knowledge and attitudes toward AD among the general public in Chongqing to inform effective public health strategies. Methods: A multistage stratified random sampling approach was employed to recruit 5,994 permanent residents aged 18 years and above from 17 districts in Chongqing between November and December 2024. Face-to-face interviews were conducted via the Chinese versions of the Alzheimer\u2019s Disease Knowledge Scale (ADKS) and the Dementia Attitudes Scale (DAS). Descriptive statistics and multivariable linear regression models were used to analyze the data and identify factors influencing AD knowledge and attitudes. Results: The mean ADKS score was 16.81 (55.78% accuracy), indicating low AD knowledge among participants. Knowledge was highest regarding the life impact but lowest concerning caregiving, symptoms, and risk factors. The mean DAS score was 78.61 (SD = 10.709), reflecting generally positive attitudes toward dementia patients. Multivariable analysis revealed that ethnic minority status (odds ratio [OR] = 0.718, 95% CI: 0.561\u20130.918), junior high school education (OR = 1.261, 95% CI: 1.055\u20131.507), high school\/vocational education (OR = 1.703, 95% CI: 1.277\u20132.271), associate or bachelor\u2019s degrees or higher (OR = 2.624, 95% CI: 1.805\u20133.815), institution\/enterprise-related personnel (OR = 1.461, 95% CI: 1.003\u20132.127), and other workers (OR = 1.241, 95% CI: 1.024\u20131.502) were associated with AD knowledge. High school\/vocational education (OR = 3.484, 95% CI: 1.115\u201310.884), associate or bachelor\u2019s degrees (OR = 4.558, 95% CI: 1.035\u201320.075), CNY 1,000\u20132,999 (OR = 3.731, 95% CI: 1.905\u20137.309), CNY 3,000\u20135,999 (OR = 14.973, 95% CI: 6.091\u201336.811), above CNY 6,000 (OR = 10.761, 95% CI: 2.361\u201349.038), and prior dementia-related training (OR = 5.573, 95% CI: 2.185\u201314.210) were associated with more positive attitudes toward dementia patients. However, production\/transport personnel (OR = 0.157, 95% CI: 0.054\u20130.453) and other workers (OR = 0.182, 95% CI: 0.085\u20130.387) presented lower DAS scores. Conclusion: This study highlights significant gaps in AD knowledge and attitudes among the Chongqing public, emphasizing the need for targeted interventions to improve awareness and reduce stigma, particularly among underserved populations. <\/jats:p>","DOI":"10.1159\/000547358","type":"journal-article","created":{"date-parts":[[2025,7,11]],"date-time":"2025-07-11T16:00:45Z","timestamp":1752249645000},"page":"441-450","source":"Crossref","is-referenced-by-count":1,"title":["Public Knowledge of Alzheimer\u2019s Disease and Attitudes toward Alzheimer\u2019s Disease in Chongqing, China: A Cross-Sectional Analysis"],"prefix":"10.1159","volume":"59","author":[{"given":"Qing-Qing","family":"Yang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ting","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li-Ling","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wu","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xian-Bin","family":"Ding","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xian-Xian","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2025,7,10]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2018.01.022"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)11667-9"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jproteome.1c00290"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.lanwpc.2024.101158"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-2667(20)30185-7"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1002\/alz.14254"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jalz.2017.12.006"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.14283\/jpad.2021.15"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(24)01296-0"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-022-14828-9"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1097\/NMD.0000000000001785"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000003727"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-024-19289-w"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1017\/S1041610221000053"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph16244882"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1136\/gpsych-2022-100751"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1186\/s12877-018-0821-4"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.7189\/jogh.14.04161"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.2147\/IJGM.S373447"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1590\/0004-282X20180106"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-021-11231-8"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1177\/1533317510394157"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1016\/j.nrleng.2018.03.004"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1007\/s10823-014-9229-6"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1097\/WAD.0000000000000102"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1177\/1471301218805923"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1016\/j.lanwpc.2021.100322"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1111\/psyg.12722"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1080\/13557858.2022.2045907"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.3760\/cma.j.cn112150-20220513-00478"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.2147\/DMSO.S290639"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0292271"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1111\/phn.13354"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.2147\/JMDH.S443189"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1002\/gps.5981"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1016\/j.nedt.2016.08.031"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1016\/j.pmedr.2023.102384"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.1589\/jpts.27.3641"},{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.3310\/nihropenres.13671.2"},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.1017\/S2045796016000159"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.1111\/psyg.12918"},{"key":"ref42","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-215262"},{"key":"ref43","doi-asserted-by":"publisher","DOI":"10.1007\/s11357-022-00711-3"}],"container-title":["Neuroepidemiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000547358","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T16:06:03Z","timestamp":1759766763000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000547358"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,10]]},"references-count":43,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2025,10,6]]}},"URL":"https:\/\/doi.org\/10.1159\/000547358","archive":["Portico"],"relation":{},"ISSN":["0251-5350","1423-0208"],"issn-type":[{"value":"0251-5350","type":"print"},{"value":"1423-0208","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,10]]}}}