{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T17:12:21Z","timestamp":1757610741892,"version":"3.44.0"},"reference-count":26,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2025,9,3]],"date-time":"2025-09-03T00:00:00Z","timestamp":1756857600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,9,3]],"date-time":"2025-09-03T00:00:00Z","timestamp":1756857600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["GE Port J Gastroenterol"],"abstract":"<jats:p>Background\/Aims: To minimize the risk of post-procedure complications, air cholangiography has been proposed as an alternative to contrast cholangiography in patients with hilar biliary obstruction undergoing endoscopic retrograde cholangiography (ERCP). We compared the rate of post-ERCP complication between these two groups. Methods: We systematically reviewed all studies that compared the safety, success, and complication rate of air versus contrast cholangiography in malignant hilar obstruction patients. Results: A total of six studies consisting of 450 patients were included in the analysis. The overall rate of post-ERCP complication was less in the air cholangiography group (relative risk [RR]: 0.43, 95% CI: 0.30\u20130.61, I2: 1.97%) compared to the contrast cholangiography group. Compared to contrast cholangiography, the pooled risk of post-ERCP cholangitis was significantly lower in the air cholangiography group (RR: 0.25, 95% CI: 0.14\u20130.44, I2: 0%). There was no difference in risk of post-ERCP pancreatitis (RR: 0.79, 95% CI: 0.32\u20131.94, I2: 0%), bleeding (RR: 1.17, 95% CI: 0.30\u20134.54), and 30-day mortality (RR: 0.59, 95% CI: 0.23\u20131.50, I2: 0%) between the two groups. The pooled odds of clinical (odds ratio [OR]: 1.14, 95% CI: 0.39\u20133.34, I2: 0%) and technical success (OR: 2.91, 95% CI: 0.52\u201316.35, I2: 0%) were similar between both groups. Conclusion: In comparison to contrast cholangiography, air cholangiography had a better safety profile and a lower rate of post-ERCP complications. <\/jats:p>","DOI":"10.1159\/000547420","type":"journal-article","created":{"date-parts":[[2025,9,3]],"date-time":"2025-09-03T16:00:47Z","timestamp":1756915247000},"page":"1-12","source":"Crossref","is-referenced-by-count":0,"title":["Air Cholangiography versus Contrast Cholangiography in Patients with Hilar Biliary Obstruction: A Systematic Review and Meta-Analysis"],"prefix":"10.1159","author":[{"given":"Zahid Ijaz","family":"Tarar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Umer","family":"Farooq","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mustafa","family":"Gandhi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdallah","family":"El Alayli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahtshamullah","family":"Chaudhry","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Faisal","family":"Kamal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Baltej","family":"Singh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yezaz A.","family":"Ghouri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nirav","family":"Thosani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2025,9,3]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.3109\/00365521.2013.779745"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1007\/s005340050166"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.suronc.2005.05.004"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1007\/s00535-010-0298-1"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-016-4993-8"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.4251\/wjgo.v13.i12.2050"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1136\/gut.32.6.685"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1097\/00042737-199705000-00013"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1136\/gut.35.4.467"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1046\/j.1445-2197.2003.02748.x"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.l4898"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.39489.470347.AD"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.21037\/qims-21-462"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1007\/s00423-009-0548-y"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1007\/s12664-014-0516-5"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1177\/1756283X15618132"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1186\/s12876-020-01341-9"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.10768"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000008372"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1055\/s-0043-1768701"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2010.02.042"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1080\/20961790.2016.1252898"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1007\/BF01296423"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2005.03.010"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1007\/BF01296439"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.5152\/tjg.2014.7526"}],"container-title":["GE - Portuguese Journal of Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000547420","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,3]],"date-time":"2025-09-03T16:00:47Z","timestamp":1756915247000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000547420"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,3]]},"references-count":26,"URL":"https:\/\/doi.org\/10.1159\/000547420","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.29598407","asserted-by":"subject"}]},"ISSN":["2341-4545","2387-1954"],"issn-type":[{"type":"print","value":"2341-4545"},{"type":"electronic","value":"2387-1954"}],"subject":[],"published":{"date-parts":[[2025,9,3]]}}}