{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T12:40:28Z","timestamp":1784205628440,"version":"3.55.0"},"reference-count":6,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2025,7,28]],"date-time":"2025-07-28T00:00:00Z","timestamp":1753660800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,7,28]],"date-time":"2025-07-28T00:00:00Z","timestamp":1753660800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Rep Ophthalmol"],"abstract":"<jats:p>&lt;p&gt;Introduction: Neuro-retinitis is a rare ocular manifestation of disseminated tuberculosis (TB), often presenting with optic disc swelling and a macular star. Early diagnosis is essential to prevent permanent visual impairment, especially in TB-endemic areas where such presentations may be overlooked. Case Presentation: We report a case of a 38-year-old male who presented with a 2-week history of progressive, painless vision loss in the left eye. Fundoscopy revealed optic disc swelling and a macular star, suggestive of neuro-retinitis. Systemic evaluation, including chest imaging and immunologic testing, confirmed disseminated TB. Other potential infectious and autoimmune causes were excluded. The patient was initiated on standard anti-TB therapy (isoniazid, rifampicin, pyrazinamide, and ethambutol) along with oral corticosteroids. At 6-week follow-up, his visual acuity improved, and optic disc swelling had decreased. Conclusion: Neuro-retinitis may be the initial presenting feature of disseminated TB. Clinicians should consider TB in the differential diagnosis of neuro-retinitis, particularly in high-prevalence settings. Early systemic evaluation and prompt initiation of anti-TB therapy can lead to favorable visual and systemic outcomes. &lt;\/p&gt;<\/jats:p>","DOI":"10.1159\/000547671","type":"journal-article","created":{"date-parts":[[2025,7,28]],"date-time":"2025-07-28T16:02:48Z","timestamp":1753718568000},"page":"610-614","source":"Crossref","is-referenced-by-count":1,"title":["Ocular Involvement in Disseminated Tuberculosis: A Case of Neuro-Retinitis"],"prefix":"10.1159","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-3331-8138","authenticated-orcid":false,"given":"Ibrahim Nagmeldin","family":"Hassan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ghada","family":"Aljaili","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2025,7,28]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.4103\/jfcm.JFCM_106_18"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jctube.2017.01.003"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1097\/ICU.0000000000000527"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.survophthal.2016.03.001"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.tube.2020.101963"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2020.06.052"}],"container-title":["Case Reports in Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000547671","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T09:11:22Z","timestamp":1765357882000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000547671"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,28]]},"references-count":6,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,1,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000547671","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.29648855","asserted-by":"subject"}]},"ISSN":["1663-2699"],"issn-type":[{"value":"1663-2699","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,28]]}}}