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Karger AG","license":[{"start":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T00:00:00Z","timestamp":1756339200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T00:00:00Z","timestamp":1756339200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["GE Port J Gastroenterol"],"abstract":"<jats:p>Background: Pancreatic cystic neoplasms (PCNs) are lesions with malignant potential that should be addressed differently according to clinical\/morphological criteria, to ensure appropriate cancer prevention and while avoiding overtreatment. Summary: Surgical resection remains the gold standard for high-risk PCNs (at least one high-risk stigmata, multiple \u201cworrisome\u201d features), whereas low-risk PCNs should be monitored through imaging to mitigate the non-negligible risk of postoperative complications. Endoscopic ultrasound (EUS)-guided therapies, such as injection or radiofrequency, may offer a minimally invasive and effective therapeutic option particularly for patients unfit for surgery, although their impact on prognostic (i.e., mortality) remains uncertain. Key Messages: This review summarizes the latest recommendations on surgical management and post-resection follow-up of PCNs and the potential role of EUS ablation in the treatment algorithm. <\/jats:p>","DOI":"10.1159\/000548201","type":"journal-article","created":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T16:01:24Z","timestamp":1756396884000},"page":"1-12","source":"Crossref","is-referenced-by-count":0,"title":["Pancreatic Club Perspectives on Surgical Approach, Post-Resection Follow-Up, and Role of Endoscopic Ablation on Pancreatic Cystic 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