{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,14]],"date-time":"2025-10-14T00:53:56Z","timestamp":1760403236253,"version":"build-2065373602"},"reference-count":9,"publisher":"S. Karger AG","issue":"5","license":[{"start":{"date-parts":[[2025,9,2]],"date-time":"2025-09-02T00:00:00Z","timestamp":1756771200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,9,2]],"date-time":"2025-09-02T00:00:00Z","timestamp":1756771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transfus Med Hemother"],"abstract":"<jats:p>&lt;p&gt;Introduction: Many erythrocyte antibodies have been reported to cause hemolytic disease of the fetus and newborn (HDFN), but Lutheran (LU) alloantibodies are normally not involved in HDFN. Case Presentation: Here we report the obstetrical history of a 29-year-old woman with pregnancy complications due to an anti-LU1 antibody causing fetal anemia and the successful treatment with intrauterine transfusion (IUT). Nonimmune hematological causes for fetal anemia and the presence of further alloantibodies, notably antibodies against low-frequency antigens, could be ruled out. Swiss National Immunohematology Reference Laboratory in Bern carried out a monocyte monolayer assay. The monocyte index was &gt;20%, indicating the presence of a clinical relevant antibody. Conclusion: The diagnosis, acute management, and follow\u2010up of neonates with fetal anemia still represent an important area of activity for maternity\/neonatal services. To our knowledge, this is the first reported case of HDFN due to an anti-LU1 antibody requiring IUT. &lt;\/p&gt;<\/jats:p>","DOI":"10.1159\/000548244","type":"journal-article","created":{"date-parts":[[2025,9,2]],"date-time":"2025-09-02T16:00:56Z","timestamp":1756828856000},"page":"334-338","source":"Crossref","is-referenced-by-count":1,"title":["Hemolytic Disease of the Fetus and Newborn due to an Anti-LU1 (anti-Lu<sup>a<\/sup>) Alloantibody: A Case Report"],"prefix":"10.1159","volume":"52","author":[{"given":"Elke","family":"Weinig","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elke","family":"B\u00e4z","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicole","family":"Kaup","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anette","family":"St\u00fcrzel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sofia","family":"Lejon Crottet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2025,9,2]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1111\/tme.12512"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2021.04.257"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.21307\/immunohematology-2019-095"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.21307\/immunohematology-2023-010"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/92.1.89"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-994623"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1111\/vox.13105"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.1961.tb00050.x"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1046\/j.1537-2995.1982.22683068629.x"}],"container-title":["Transfusion Medicine and Hemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000548244","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T16:01:29Z","timestamp":1760371289000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000548244"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,2]]},"references-count":9,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2025,10,13]]},"published-print":{"date-parts":[[2025,10,13]]}},"URL":"https:\/\/doi.org\/10.1159\/000548244","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.30031231","asserted-by":"subject"}]},"ISSN":["1660-3796","1660-3818"],"issn-type":[{"type":"print","value":"1660-3796"},{"type":"electronic","value":"1660-3818"}],"subject":[],"published":{"date-parts":[[2025,9,2]]}}}