{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T08:49:45Z","timestamp":1770713385869,"version":"3.49.0"},"reference-count":19,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2025,9,8]],"date-time":"2025-09-08T00:00:00Z","timestamp":1757289600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2025,9,8]],"date-time":"2025-09-08T00:00:00Z","timestamp":1757289600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Fetal Diagn Ther"],"abstract":"<jats:p>Introduction: The aim of this study was to evaluate the outcomes with lung changes of fetoscopic endoluminal tracheal occlusion (FETO) for congenital diaphragmatic hernia (CDH). Methods: Between 2014 and 2023, we performed FETO for severe or moderate left-sided CDH with the Kitano grade 3 stomach position. We analyzed the pre- and postoperative ultrasound findings, pregnancy outcomes, and survival rates at 6 months. Results: Twenty-five patients were analyzed. The median gestational age at balloon insertion was 29.1 (range: 27.1\u201331.8) weeks. The median gestational age at delivery was 35.7 (range: 30.7\u201338.7) weeks. Pulmonary hypertension was observed in 71% (15\/21) of the cases. The 6-month survival rate was 40% (10\/25). The post-FETO observed-to-expected lung area-to-head circumference ratio (o\/e LHR) and differences between pre- and post-FETO values were significantly higher in survivors than in infants who died (p &lt; 0.01 and p &lt; 0.01, respectively), but pre-FETO values were not. The post-FETO cutoff value associated with the 6-month survival was 33.8%, and that of the difference between pre- and post-FETO o\/e LHR was 7.8% (area under the curve = 0.91 and 0.86, respectively). Conclusions: FETO can lead to an increased o\/e LHR in some but not all CDH fetuses, reflecting fetal lung growth, and be associated with a survival when it exceeds the threshold.<\/jats:p>","DOI":"10.1159\/000548340","type":"journal-article","created":{"date-parts":[[2025,9,8]],"date-time":"2025-09-08T16:01:06Z","timestamp":1757347266000},"page":"78-88","source":"Crossref","is-referenced-by-count":0,"title":["The Outcomes and Lung Changes of Fetoscopic Endoluminal Tracheal Occlusion in Fetus with Diaphragmatic Hernia: A Single-Center Experience in Japan"],"prefix":"10.1159","volume":"53","author":[{"given":"Jin","family":"Muromoto","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katsusuke","family":"Ozawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rika","family":"Sugibayashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shoichiro","family":"Amari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seiji","family":"Wada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yutaka","family":"Kanamori","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yushi","family":"Ito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9387-1849","authenticated-orcid":false,"given":"Haruhiko","family":"Sago","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2025,9,8]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2014-306174"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2021.11.1351"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e31823d3aea"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1002\/pd.6207"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2522081955"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000005491"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2022.05.011"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1002\/pd.5062"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2027030"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajogmf.2023.101248"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1111\/jog.14504"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2007.05.034"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1002\/uog.4052"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1002\/uog.8892"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3468(94)90328-x"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.3109\/14767058.2015.1114080"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1002\/jcu.23121"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1002\/pd.4642"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1002\/uog.26164"}],"container-title":["Fetal Diagnosis and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000548340","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T14:51:00Z","timestamp":1770648660000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000548340"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,8]]},"references-count":19,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,2,9]]},"published-print":{"date-parts":[[2026,2,10]]}},"URL":"https:\/\/doi.org\/10.1159\/000548340","archive":["Portico"],"relation":{},"ISSN":["1015-3837","1421-9964"],"issn-type":[{"value":"1015-3837","type":"print"},{"value":"1421-9964","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9,8]]}}}