{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T00:54:24Z","timestamp":1760576064505,"version":"build-2065373602"},"reference-count":10,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T00:00:00Z","timestamp":1757376000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T00:00:00Z","timestamp":1757376000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Haematol"],"abstract":"<jats:p>Introduction: Nodular lymphocyte-predominant Hodgkin\u2019s lymphoma (NLPHL) often follows an indolent course but carries a risk of late recurrence and transformation. Given its rarity, there is significant variability in the treatment patterns at various healthcare centers. Methods: This retrospective chart review aimed to compare the patient characteristics and outcomes of NLPHL patients &gt;18 years of age diagnosed between January 1st, 2007, and December 31st, 2022, at Parkland Health, the safety-net system for uninsured\/underinsured patients in Dallas County, with patients treated at the neighboring NCI-designated Harold C. Simmons Comprehensive Cancer Center (SCCC). Results: Our cohort included 53 adult patients (25 at PH vs. 28 at SCCC). PH patients were more likely to belong to racial\/ethnic minority groups (black non-Hispanic 84% at PH vs. 32% at SCCC, Hispanic 16% at PH vs. 0% at SCCC, p &lt; 0.01) and to be uninsured (60% at PH vs. 0% at SCCC, p &lt; 0.01). Site of care (PH vs. SCCC) or race\/ethnicity did not impact the treatment choice. At a median follow-up of 60 months (IQR 21\u201383), 3 deaths occurred, resulting in an overall 5-year restricted mean overall survival of 57 months. Overall survival and progression-free survival were not statistically different between the two sites of treatment. Conclusion: Despite health inequities that typically impact safety-net patients, we did not observe differences in treatment patterns or outcomes of Nodular lymphocyte-predominant Hodgkin\u2019s lymphoma between patients treated at PH compared to SCCC. <\/jats:p>","DOI":"10.1159\/000548357","type":"journal-article","created":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T16:00:45Z","timestamp":1757433645000},"page":"1-6","source":"Crossref","is-referenced-by-count":0,"title":["Patient Characteristics and Outcomes of Nodular Lymphocyte-Predominant Hodgkin\u2019s Lymphoma at a Safety-Net System Compared to an Academic Comprehensive Cancer Center"],"prefix":"10.1159","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0569-4278","authenticated-orcid":false,"given":"Luise","family":"Froessl","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Theo","family":"Sottero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L. Steven","family":"Brown","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hsiao C.","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Radhika","family":"Kainthla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Navid","family":"Sadeghi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2025,9,9]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.19.00986"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.29527"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.23.01655"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.18169"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.3109\/10428194.2012.708751"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2018-10-877761"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2014.60.4363"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2017-02-766121"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1097\/HS9.0000000000000837"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2013-12-541078"}],"container-title":["Acta Haematologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000548357","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T16:01:12Z","timestamp":1760544072000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000548357"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,9]]},"references-count":10,"URL":"https:\/\/doi.org\/10.1159\/000548357","archive":["Portico"],"relation":{},"ISSN":["0001-5792","1421-9662"],"issn-type":[{"type":"print","value":"0001-5792"},{"type":"electronic","value":"1421-9662"}],"subject":[],"published":{"date-parts":[[2025,9,9]]}}}