{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T17:48:38Z","timestamp":1777398518663,"version":"3.51.4"},"reference-count":31,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T00:00:00Z","timestamp":1757894400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T00:00:00Z","timestamp":1757894400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiology"],"abstract":"<jats:p>Introduction: Acute type A aortic dissection (TAAD) mandates urgent surgery, yet postoperative acute lung injury (ALI) remains common and worsens outcomes. We aimed to identify perioperative predictors of ALI and develop a practical risk prediction model to enable early stratification and targeted prevention. Methods: The clinical data of patients who underwent TAAD in the First Affiliated Hospital of Nanchang University from January 2022 to June 2024 were retrospectively analyzed. According to whether ALI occurred after surgery, ALI group and non-ALI group were divided into two groups. Univariate and multivariate analyses were performed on the factors that may cause ALI, and multivariate logistic regression prediction model was constructed. Results: A total of 187 patients were included in the study, including 94 patients in the non-ALI group and 93 patients in the ALI group. The incidence of ALI after TAAD was 49.7%. Multivariate analysis showed that BMI, smoking history, D-dimer, interleukin-6, and cardiopulmonary bypass time were independent risk factors for ALI after TAAD. The prediction model based on these risk factors has good prediction efficiency. Conclusion: BMI, smoking history, D-dimer, interleukin-6, and cardiopulmonary bypass time are independent risk factors for ALI after TAAD. The predictive model established based on these risk factors has good predictive efficacy, which helps identify high-risk patients early, take appropriate preventive measures, improve surgical safety, and improve patient prognosis.<\/jats:p>","DOI":"10.1159\/000548374","type":"journal-article","created":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T16:00:42Z","timestamp":1757952042000},"page":"1-13","source":"Crossref","is-referenced-by-count":1,"title":["Risk Factor Analysis and Prediction of Acute Postoperative Lung Injury after Type A Aortic Dissection"],"prefix":"10.1159","author":[{"given":"Mingming","family":"Yuan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shansong","family":"Gao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuqin","family":"Zhong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianfeng","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoming","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qicai","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2025,9,15]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccl.2017.03.004"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1177\/02184923221083365"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2021.04.053"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.23736\/s0021-9509.20.11293-x"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.52198\/21.sti.38.cv1413"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1186\/s12872-022-02579-9"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2024.05.019"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezae176"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1186\/s13019-024-02775-y"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1093\/pnasnexus\/pgae371"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.2174\/1566524018666180222123518"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.21037\/jtd-22-1122"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-15859-3"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-019-05594-1"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2021.08.001"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.3390\/life14080955"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1186\/s13019-022-02080-6"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2022.1004005"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1136\/thoraxjnl-2020-216296"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1007\/s00424-023-02805-z"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00482.2018"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1007\/s11239-024-02995-y"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2021.644903"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1007\/s00408-018-0150-6"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2023.110618"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1007\/s10517-018-4042-9"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2023.1093616"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1097\/js9.0000000000000434"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1186\/s12872-023-03664-3"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics12061424"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1055\/s-0042-1757573"}],"container-title":["Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000548374","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T17:00:55Z","timestamp":1762448455000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000548374"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,15]]},"references-count":31,"URL":"https:\/\/doi.org\/10.1159\/000548374","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.30112408","asserted-by":"subject"}]},"ISSN":["0008-6312","1421-9751"],"issn-type":[{"value":"0008-6312","type":"print"},{"value":"1421-9751","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9,15]]}}}