{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T17:53:17Z","timestamp":1784742797185,"version":"3.55.0"},"reference-count":9,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T00:00:00Z","timestamp":1762473600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T00:00:00Z","timestamp":1762473600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatology"],"abstract":"<jats:p>Introduction: Accurate visualization of nail\u2010matrix psoriasis remains challenging. Ultraviolet-fluorescence dermoscopy (UVF-D) may enhance detection, yet rigorous comparative data are scarce. The aim of this study was to compare the diagnostic yield of UVF-D with standard dermoscopy and naked-eye clinical examination for matrix and bed involvement in nail psoriasis. Methods: In this single-centre prospective pilot study (March\u2013July 2024), 35 consecutive adults with plaque psoriasis underwent triplicate assessment (clinical, dermoscopy, UVF-D) of all fingernails. Each nail quadrant was scored for matrix-Nail Psoriasis Severity Index (NAPSI) and bed-NAPSI by two blinded dermatologists in randomized order. The study was powered (80%, \u03b1 = 0.05) to detect a \u22653-point mean difference in matrix-NAPSI between modalities. Results: UVF-D identified matrix involvement in 550\/1,400 quadrants (39.3%) versus 448\/1,400 (32.0%) with standard dermoscopy and 441\/1,400 (31.5%) clinically (p &lt; 0.001; Kendall\u2019s W = 0.42). Mean \u00b1 SD matrix-NAPSI scores were 15.7 \u00b1 5.3 (UVF-D), 12.8 \u00b1 5.2 (dermoscopy), and 12.6 \u00b1 4.8 (clinical). Thus, UVF-D detected roughly one additional matrix-affected quadrant for every seven examined and produced a higher matrix-NAPSI, underscoring its added sensitivity over conventional methods. Conclusions: UVF-D significantly improves visualization of nail-matrix psoriasis versus standard approaches. Larger multicentre studies should validate its diagnostic and longitudinal utility.<\/jats:p>","DOI":"10.1159\/000549051","type":"journal-article","created":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T17:01:19Z","timestamp":1762534879000},"page":"16-22","source":"Crossref","is-referenced-by-count":1,"title":["Quadrant-Based Comparison of Ultraviolet-Fluorescence Dermoscopy, Standard Dermoscopy, and Clinical Examination in Adults with Nail Psoriasis: A Prospective Pilot Study of 35 Patients"],"prefix":"10.1159","volume":"242","author":[{"given":"Gozde","family":"Simsek","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ismail Hakki","family":"Unal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aslan","family":"Yurekli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eda","family":"Karaismailoglu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9483-6268","authenticated-orcid":false,"given":"Gulsen","family":"Akoglu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2025,11,7]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.5826\/dpc.1201a10"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.25259\/CSDM_198_2024"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1159\/000332974"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.4274\/turkderm.54289"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.5114\/ada.2017.65618"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1007\/s13555-024-01104-4"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1067\/s0190-9622(03)00910-1"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.4103\/0019-5154.156377"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.4103\/idoj.IDOJ_51_19"}],"container-title":["Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000549051","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T17:01:48Z","timestamp":1770138108000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000549051"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,7]]},"references-count":9,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,2,3]]},"published-print":{"date-parts":[[2026,2,4]]}},"URL":"https:\/\/doi.org\/10.1159\/000549051","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.30563189","asserted-by":"subject"}]},"ISSN":["1018-8665","1421-9832"],"issn-type":[{"value":"1018-8665","type":"print"},{"value":"1421-9832","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,7]]}}}