{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T20:06:34Z","timestamp":1791576394129,"version":"4.3.4"},"reference-count":47,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T00:00:00Z","timestamp":1760745600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T00:00:00Z","timestamp":1760745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Blood Purif"],"abstract":"Background: Sodium management during hemodialysis session is based on the dialysate sodium (Na<sub>D<\/sub>) prescription by the physician. However, the conflicting results of studies concerning the relationship between Na<sub>D<\/sub> and mortality, and the sometimes significant difference between the Na<sub>D<\/sub> prescribed and its actual value, are barriers to issuing on the optimal Na<sub>D<\/sub> value. In the absence of any rational justification for preferring high or low dialysate sodium, prescribing Na<sub>D<\/sub> remains empirical and quite intuitive. Summary: From a clinical perspective, several arguments suggest prescribing the change in natremia (\u0394Na) to be achieved at the end of the dialysis session rather than the Na<sub>D<\/sub> value. Conductivity monitoring allows to calculate an online estimate (Na<sub>Cond<\/sub>) of natremia and makes the hemodialysis monitor able to automatically adjust Na<sub>D<\/sub> to achieve a Na<sub>Cond<\/sub> target. From a technical standpoint, prescribing a Na<sub>Cond<\/sub>-change target (\u0394Na<sub>Cond<\/sub>) rather than a Na<sub>Cond<\/sub> target has the major advantage that the \u0394Na<sub>Cond<\/sub> value obtained at the end of the session may be unaffected by any lack of accuracy in the Na<sub>D<\/sub> value. Key-Messages: Prescribing a target change (\u0394Na) in natremia appears to be more rational and clinically relevant than prescribing a dialysate sodium. Conductivity monitoring makes it easier to implement this prescription in everyday clinical practice.<\/jats:p>","DOI":"10.1159\/000549090","type":"journal-article","created":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T16:00:45Z","timestamp":1760803245000},"page":"156-160","source":"Crossref","is-referenced-by-count":2,"title":["Prescribing Dialysate Sodium in Maintenance Hemodialysis Patients: What Can Conductivity Monitoring 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