{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T17:05:33Z","timestamp":1767200733286,"version":"3.48.0"},"reference-count":12,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2025,11,29]],"date-time":"2025-11-29T00:00:00Z","timestamp":1764374400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,11,29]],"date-time":"2025-11-29T00:00:00Z","timestamp":1764374400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Rep Dermatol"],"abstract":"<jats:p>Introduction: Leprosy, caused by Mycobacterium leprae, is primarily characterized by cutaneous and peripheral nerve involvement. Nonetheless, musculoskeletal manifestations are also frequently observed and are commonly misdiagnosed as rheumatic diseases. Case Presentation: We report a case of lepromatous leprosy presenting with chronic arthritis and HLA-B27 positivity, which was misdiagnosed as peripheral spondyloarthritis in the early stage due to the absence of typical clinical manifestations. Conclusion: Lepromatous leprosy may mimic peripheral spondyloarthritis, especially with HLA-B27 positivity. Clinicians should consider leprosy in refractory arthritis or neuropathy, even in non-endemic areas, to prevent disability and transmission.<\/jats:p>","DOI":"10.1159\/000549460","type":"journal-article","created":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T17:11:44Z","timestamp":1764609104000},"page":"11-17","source":"Crossref","is-referenced-by-count":0,"title":["HLA-B27-Positive Leprosy Masquerading as Peripheral Spondyloarthritis: A Case Report"],"prefix":"10.1159","volume":"18","author":[{"given":"Qian","family":"Peng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Afang","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qijing","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaobing","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2025,11,29]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-025-07474-0"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1038\/nrrheum.2015.133"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.berh.2019.02.010"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.47276\/lr.84.1.65"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.47276\/lr.79.4.372"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.3889\/oamjms.2021.7629"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1136\/rmdopen-2018-000802"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2024.116622"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2022-250835"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1007\/s00281-020-00790-4"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.berh.2025.102039"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1177\/1759720X18773726"}],"container-title":["Case Reports in Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000549460","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T17:00:57Z","timestamp":1767200457000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000549460"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,29]]},"references-count":12,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,1,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000549460","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.30740933","asserted-by":"subject"}]},"ISSN":["1662-6567"],"issn-type":[{"type":"electronic","value":"1662-6567"}],"subject":[],"published":{"date-parts":[[2025,11,29]]}}}