{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T05:20:01Z","timestamp":1773120001762,"version":"3.50.1"},"reference-count":51,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T00:00:00Z","timestamp":1768262400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T00:00:00Z","timestamp":1768262400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Complement Med Res"],"abstract":"<jats:p>Hintergrund: Standardisierte Ginkgo-biloba-Extrakte werden h\u00e4ufig zur Behandlung von Demenz, Tinnitus, Schwindel und peripherer arterieller Verschlusskrankheit eingesetzt. Dar\u00fcber hinaus gibt es zahlreiche Off-Label-Anwendungen. Zusammenfassung: Ginkgo-biloba-Extrakte weisen antioxidative, neuroprotektive und durchblutungsf\u00f6rdernde Eigenschaften auf. Studien deuten darauf hin, dass sie positive Effekte auf die kognitive Leistungsf\u00e4higkeit, die Stresshormonregulation und die Endothelfunktion haben. Erforscht wird ihre potenzielle Rolle bei Stressbew\u00e4ltigung, Angstst\u00f6rung, unipolarer Depression, Schlafst\u00f6rungen, Herz-Kreislauf-Erkrankungen, Augenerkrankungen und erektiler Dysfunktion. Kernaussagen: Ginkgo-biloba-Extrakte k\u00f6nnten \u00fcber ihre antioxidativen und neuroprotektiven Effekte therapeutische Vorteile bei Off-Label-Anwendungen bieten. Die vielversprechenden Ergebnisse klinischer Studien deuten auf eine potenzielle Wirksamkeit bei psychischen und kardiovaskul\u00e4ren Erkrankungen, Augenerkrankungen und erektiler Dysfunktion hin. Weitere randomisierte, kontrollierte Studien sind erforderlich, um die langfristige Sicherheit und Wirksamkeit in diesen Off-Label-Indikationen zu best\u00e4tigen.<\/jats:p>","DOI":"10.1159\/000549638","type":"journal-article","created":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T17:00:50Z","timestamp":1768323650000},"page":"1-10","source":"Crossref","is-referenced-by-count":0,"title":["Off-Label-Anwendungen standardisierter 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