{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T06:53:01Z","timestamp":1783666381661,"version":"3.55.0"},"reference-count":13,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T00:00:00Z","timestamp":1768780800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T00:00:00Z","timestamp":1768780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Rep Ophthalmol"],"abstract":"<jats:p>Introduction: Sickle cell disease is associated with painful vaso-occlusive crises, bone infarction, avascular necrosis, and osteomyelitis. Sickle cell orbitopathy is a rare manifestation with signs similar to periorbital cellulitis and has subtle radiologic features. Case Presentation: We report a case of a five-year-old girl with sickle cell who presented with bilateral orbital infarctions and subperiosteal hematomas, notably without periorbital pain, and was treated with antibiotics and steroids. Conclusion: Physicians should be aware of this rare manifestation, especially in the pediatric population, as it can affect subsequent management.<\/jats:p>","DOI":"10.1159\/000550138","type":"journal-article","created":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T17:00:50Z","timestamp":1768842050000},"page":"156-161","source":"Crossref","is-referenced-by-count":1,"title":["Sickle Cell Crisis-Induced Painless Bilateral Orbital Bone Infarction: A Case Report"],"prefix":"10.1159","volume":"17","author":[{"given":"Luke","family":"Farson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina","family":"Shenouda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agni","family":"Kakouri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashkan","family":"Kashanchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clark","family":"Sitton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy","family":"McCulley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2026,1,19]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1510865"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2022.10233"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.14423\/SMJ.0000000000000516"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1038\/eye.2001.248"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1080\/17843286.2015.1107206"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2008.05.041"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.12659\/AJCR.939595"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/5867850"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1159\/000532016"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2021.280105"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1097\/IOP.0b013e31816b960e"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1097\/00000441-199108000-00008"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1002\/ccr3.5994"}],"container-title":["Case Reports in Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000550138","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T17:00:52Z","timestamp":1771002052000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000550138"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,19]]},"references-count":13,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,1,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000550138","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.31017142","asserted-by":"subject"}]},"ISSN":["1663-2699"],"issn-type":[{"value":"1663-2699","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,19]]}}}