{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T16:19:41Z","timestamp":1783354781327,"version":"3.54.6"},"reference-count":23,"publisher":"S. Karger AG","issue":"7","license":[{"start":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T00:00:00Z","timestamp":1768176000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T00:00:00Z","timestamp":1768176000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Respiration"],"abstract":"<jats:p>&lt;p&gt;Introduction: There are limited data on the prevalence and treatment of low bone density in young lung transplant recipients (LTRs), even though osteoporosis is common in patients with end-stage lung disease and transplant recipients. This study aimed to assess bone health in young LTRs. Methods: We retrospectively reviewed medical records for LTRs aged 18\u201350 at transplant. Outcomes included posttransplant low bone density (Z score &lt; \u22122), osteoporotic fractures, and treatment data. Results: Among 150 LTRs (45% female, mean age 38 \u00b1 9 years), with a median follow-up of 6.2 years, 103 (69%) underwent bone density scans; 82 occurred within the first year posttransplant. Of these, 19 (23%) showed low bone density within the first year. Posttransplant osteoporotic fractures occurred in 34 patients (23%), including femoral neck (32%) and vertebral fractures (29%) as first events. Eleven patients (32%) experienced multiple fractures. Pretransplant fracture history significantly predicted posttransplant fractures (HR 6.720, 95% CI: 1.572\u201328.724). Osteoporosis treatment was given to 41 patients (27%), primarily with bisphosphonates (93% as first line). Of those treated, 49% remained fracture free during follow-up. Conclusion: Young LTRs face high rates of low bone density and fractures, including serious and recurrent fractures. These findings underscore the need for early screening and intervention to reduce osteoporosis-related morbidity in this vulnerable population. &lt;\/p&gt;<\/jats:p>","DOI":"10.1159\/000550456","type":"journal-article","created":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T17:01:15Z","timestamp":1768237275000},"page":"763-774","source":"Crossref","is-referenced-by-count":0,"title":["Bone Health in Young Lung Transplant Recipients: A Retrospective Study"],"prefix":"10.1159","volume":"105","author":[{"given":"Aviva","family":"Lerman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5173-0578","authenticated-orcid":false,"given":"Osnat","family":"Shtraichman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3220-6321","authenticated-orcid":false,"given":"Yaron","family":"Rudman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mordechai R.","family":"Kramer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Idit","family":"Dotan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2033-7300","authenticated-orcid":false,"given":"Gloria","family":"Tsvetov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6211-2073","authenticated-orcid":false,"given":"Talia","family":"Diker Cohen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2026,1,12]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.4158\/GL-2020-0524SUPPL"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2019.07.006"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.96.09112378"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/573041"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.3390\/jcm9092941"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-015-3367-8"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2025.01.010"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp1800214"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1093\/ejendo\/lvae146"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2016.06.008"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2012.09.117"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.162.3.2002051"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.3803\/EnM.2024.1939"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1007\/s001980170112"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2009.1462"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1186\/s12877-016-0332-0"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2021.07.005"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2004.03.024"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1210\/endrev\/bnac031"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1007\/s00223-022-00949-1"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.3275\/8617"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1007\/s11657-013-0167-7"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-024-07052-1"}],"container-title":["Respiration"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000550456","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T16:01:23Z","timestamp":1783353683000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000550456"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,12]]},"references-count":23,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2026,7,6]]},"published-print":{"date-parts":[[2026,7,22]]}},"URL":"https:\/\/doi.org\/10.1159\/000550456","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.31047409","asserted-by":"subject"}]},"ISSN":["0025-7931","1423-0356"],"issn-type":[{"value":"0025-7931","type":"print"},{"value":"1423-0356","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,12]]}}}