{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T16:56:07Z","timestamp":1776185767172,"version":"3.50.1"},"reference-count":19,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T00:00:00Z","timestamp":1773360000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T00:00:00Z","timestamp":1773360000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Haematol"],"abstract":"<jats:p>Introduction: Newly diagnosed autoimmune hemolytic anemia (AIHA) develops in 1\u20133 individuals per 100,000 people per year. Warm autoimmune hemolytic anemia (WAIHA) is the most common type of AIHA, accounting for approximately 70\u201380% of cases. This report outlines a complex presentation of DAT-negative, anti-e-mimicking autoantibody mediated WAIHA following a transient viral infection in an adult male patient with no prior transfusions. Case Presentation: The 55-year-old male patient presented with several weeks of flu-like symptoms followed by jaundice, dyspnea, and progressive fatigue. Initial laboratory workup revealed hemolytic anemia, and subsequent serologic testing identified a warm autoantibody with anti-C specificity, but was ultimately consistent with an anti-e mediated WAIHA. Conclusion: This report highlights a complex case of a patient with an autoantibody mimicking anti-e associated WAIHA and the challenge of identifying suitable transfusion options.<\/jats:p>","DOI":"10.1159\/000550486","type":"journal-article","created":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T17:00:44Z","timestamp":1773421244000},"page":"1-6","source":"Crossref","is-referenced-by-count":0,"title":["A Complex Case of Anti-e Mimicking Autoantibody Development Leading to Warm Autoimmune Hemolytic Anemia: Case Report"],"prefix":"10.1159","author":[{"given":"Ilsa","family":"Hale","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristina L.","family":"Kunes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2433-4844","authenticated-orcid":false,"given":"Jean","family":"Sabile","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacob","family":"Dougherty","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Trisha","family":"Wong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3790-0478","authenticated-orcid":false,"given":"Michael","family":"Heinrich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2026,3,13]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tmrv.2010.03.002"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1182\/asheducation-2016.1.690"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.3390\/ijms25084296"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2010.036053"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.blre.2019.100648"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-016-2605-2"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.3343\/alm.2013.33.5.343"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1093\/labmed\/lmaa096"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcmd.2013.12.003"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.amsu.2022.104444"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2020-139001"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.16794"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1111\/trf.16226"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1111\/tme.12965"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2019003808"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1177\/03000605241258881"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/aqad095"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.mjafi.2020.08.001"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1309\/vdax8wxdhtm3uh62"}],"container-title":["Acta Haematologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000550486","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T16:00:42Z","timestamp":1776182442000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000550486"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,13]]},"references-count":19,"URL":"https:\/\/doi.org\/10.1159\/000550486","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.31645930","asserted-by":"subject"}]},"ISSN":["0001-5792","1421-9662"],"issn-type":[{"value":"0001-5792","type":"print"},{"value":"1421-9662","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,13]]}}}