{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T19:04:29Z","timestamp":1772651069443,"version":"3.50.1"},"reference-count":11,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2026,1,26]],"date-time":"2026-01-26T00:00:00Z","timestamp":1769385600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,1,26]],"date-time":"2026-01-26T00:00:00Z","timestamp":1769385600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Glomerular Dis"],"abstract":"<jats:p>Introduction: Aristolochic acid nephropathy (AAN), a progressive form of interstitial nephritis, is predominantly associated with the oral ingestion of herbal remedies containing aristolochic acid (AA). Case Presentation: This report details a rare case of AAN linked to nasal inhalation of a traditional herbal preparation. An 80-year-old monk with chronic kidney disease and rapidly declining kidney function underwent kidney biopsy, revealing severe interstitial fibrosis, tubular atrophy, and the presence of aristolochic acid-DNA adducts, confirming the diagnosis. Further investigation uncovered prolonged use of a nasal inhalation remedy for alertness and nasal decongestion. Analysis of the preparation using liquid chromatography-diode array detection-quadrupole time-of-flight mass spectrometry identified aristolochic acid I, directly linking the remedy to the renal pathology. Conclusion: This case highlights a previously underrecognized route of AA exposure and underscores the critical importance of comprehensive history-taking, increased regulation of alternative medicines, and public awareness to prevent similar cases of nephrotoxicity.<\/jats:p>","DOI":"10.1159\/000550695","type":"journal-article","created":{"date-parts":[[2026,1,26]],"date-time":"2026-01-26T17:00:47Z","timestamp":1769446847000},"page":"52-55","source":"Crossref","is-referenced-by-count":0,"title":["Beyond Ingestion: Nasal Inhalation-Induced Aristolochic Acid Nephropathy from a Traditional Herbal Remedy \u2013 A Case Report"],"prefix":"10.1159","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2996-8934","authenticated-orcid":false,"given":"Talerngsak","family":"Kanjanabuch","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Veerapat","family":"Wattanasatja","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patnarin","family":"Kanjanabuch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suwasin","family":"Udomkarnjananun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Somchai","family":"Eiam-Ong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2026,1,26]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.11571017"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrestox.4c00157"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000026510"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1038\/ki.2008.129"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.23876\/j.krcp.22.211"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.3390\/ijms18020297"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2009.05.028"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.17132"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2023.12.012"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1177\/2042098621997727"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.3390\/ijms18102144"}],"container-title":["Glomerular Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000550695","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T17:00:43Z","timestamp":1772643643000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000550695"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,26]]},"references-count":11,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,1,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000550695","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.31143970","asserted-by":"subject"}]},"ISSN":["2673-3633"],"issn-type":[{"value":"2673-3633","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,26]]}}}