{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T20:32:55Z","timestamp":1774384375637,"version":"3.50.1"},"reference-count":4,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T00:00:00Z","timestamp":1769644800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T00:00:00Z","timestamp":1769644800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Fetal Diagn Ther"],"abstract":"<jats:p>Introduction: The objectives of this study were to evaluate the feasibility of slice-to-volume registration (SVR) of the fetal thorax in congenital diaphragmatic hernia (CDH) and to compare observed-to-expected total fetal lung volume (O\/E TFLV) obtained from original and SVR MRI volumes for prediction of postnatal survival. Methods: We retrospectively analyzed 35 fetuses with CDH undergoing MRI before and after fetoscopic endoluminal tracheal occlusion (FETO). High-resolution, motion-corrected SVR volumes were reconstructed using an automated pipeline. O\/E TFLV was measured on both original and SVR volumes, and results were compared between survivors and non-survivors at 6 months of age. Agreement, correlation, and predictive accuracy were assessed using Pearson correlation and ROC analysis. Results: Four (11.4%) cases were excluded due to uncorrectable artifacts or technical issues. SVR reconstruction required only three acquisitions versus a median of six for conventional imaging. Post-processing took a median of 14 min, and lung delineation was longer for SVR than for original volumes. O\/E TFLV measurements showed good to very good agreement between original and SVR volumes (r = 0.75 before and r = 0.96 after FETO), with comparable predictive accuracy for survival (AUC original = 0.81\u20130.83 vs. AUCSVR = 0.83, p &gt; 0.7). Conclusion: SVR of the fetal thorax is feasible in CDH and provides reliable O\/E TFLV measurements with prognostic accuracy comparable to conventional MRI, while reducing the need for repeated acquisitions.<\/jats:p>","DOI":"10.1159\/000550698","type":"journal-article","created":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T17:01:07Z","timestamp":1769706067000},"page":"1-5","source":"Crossref","is-referenced-by-count":0,"title":["Slice-to-Volume Registration of the Fetal Thorax to Assess Observed\/Expected Total Fetal Lungs Volume in Fetuses with Congenital Diaphragmatic Hernia Who Underwent Fetoscopic Endoluminal Tracheal Occlusion"],"prefix":"10.1159","author":[{"given":"Romain","family":"Corroenne","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pamela M.","family":"Ketwaroo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Magdalena","family":"Sanz Cortes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2026,1,29]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-022-04540-6"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.219.1.r01ap18236"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/J.MEDIA.2022.102484"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.17.19469"}],"container-title":["Fetal Diagnosis and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000550698","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T17:01:15Z","timestamp":1774371675000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000550698"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,29]]},"references-count":4,"URL":"https:\/\/doi.org\/10.1159\/000550698","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.31156948","asserted-by":"subject"}]},"ISSN":["1015-3837","1421-9964"],"issn-type":[{"value":"1015-3837","type":"print"},{"value":"1421-9964","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,29]]}}}