{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T16:51:49Z","timestamp":1776271909660,"version":"3.50.1"},"reference-count":24,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T00:00:00Z","timestamp":1772064000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T00:00:00Z","timestamp":1772064000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Digestion"],"abstract":"<jats:p>Introduction: In patients with acute cholecystitis and choledocholithiasis undergoing endoscopic retrograde cholangiopancreatography (ERCP) followed by interval cholecystectomy (6 weeks\u20133 months), preoperative biliopancreatic events are reported in 18.3\u201341.8%. Endoscopic transpapillary gallbladder drainage (ET-GBD) is indicated in this patient group if there are comorbidities preventing surgery. This study compared biliopancreatic events during the interval to cholecystectomy in patients who underwent ET-GBD despite being surgically fit versus those treated with ERCP alone. Methods: In this retrospective study conducted between 2018 and 2023, 121 patients with cholecystitis secondary to choledocholithiasis underwent ERCP. Surgical candidates expected to undergo delayed cholecystectomy were divided into two groups: those who received ET-GBD (study group) and those who did not (control group, from the first half of the study period). Results: The ET-GBD group had a mean age of 54.54 (56.7% female), while the non-ET-GBD group had a mean age of 63.18 (50% female). During the waiting period, biliopancreatic events occurred in 1\/34 (2.9%) of ET-GBD patients versus 18\/34 (52.9%) of controls (absolute risk reduction: 50.0%, 95% confidence interval [CI]: 21.8\u201368.0; relative risk: 0.056, 95% CI: 0.0079\u20130.39; p &lt; 0.001). Specifically, biliary colic (2.9% vs. 47.1%; p &lt; 0.001), cholecystitis (0% vs. 17.6%; p = 0.009), and choledocholithiasis (0% vs. 26.4%; p = 0.001) were significantly less frequent in the ET-GBD group. Conclusion: ET-GBD was associated with significantly lower biliopancreatic complications during the interval to surgery in operable patients with acute cholecystitis and choledocholithiasis.<\/jats:p>","DOI":"10.1159\/000551128","type":"journal-article","created":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T17:00:46Z","timestamp":1772125246000},"page":"1-10","source":"Crossref","is-referenced-by-count":0,"title":["Endoscopic Transpapillary Gallbladder Drainage Reduces the Frequency of Biliopancreatic Events in the Waiting Period for Surgery, Even in Patients without Comorbid Diseases"],"prefix":"10.1159","author":[{"given":"Yavuz Emre","family":"Parlar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bengi","family":"\u00d6zt\u00fcrk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Onur","family":"Keskin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taylan","family":"Kav","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erkan","family":"Parlak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2026,2,26]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1007\/s00534-012-0567-x"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1111\/jgh.15065"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.5946\/ce.2015.48.5.411"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1002\/jhbp.967"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2020.06.066"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1111\/den.12799"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1186\/s13017-020-00336-x"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-023-10423-0"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11216603"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v12.i6.956"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2024.02.007"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1186\/s43055-021-00579-x"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/s0016-5107(91)70740-2"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/s0002-9610(01)00849-2"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2010.01.026"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.5009\/gnl14070"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2008.02.052"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1007\/s00534-012-0570-2"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2015.08.072"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.5009\/gnl20238"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.5946\/ce.2021.023"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.3390\/gastroent12040039"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10214842"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1055\/s-0044-102091"}],"container-title":["Digestion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000551128","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T16:00:51Z","timestamp":1776268851000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000551128"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,26]]},"references-count":24,"URL":"https:\/\/doi.org\/10.1159\/000551128","archive":["Portico"],"relation":{},"ISSN":["0012-2823","1421-9867"],"issn-type":[{"value":"0012-2823","type":"print"},{"value":"1421-9867","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,26]]}}}