{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T00:34:44Z","timestamp":1790555684580,"version":"4.1.0"},"reference-count":33,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T00:00:00Z","timestamp":1777075200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T00:00:00Z","timestamp":1777075200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Kidney Dis"],"abstract":"<jats:p>Introduction: Patients undergoing peritoneal dialysis (PD) experience exceptionally high mortality. While the cardiothoracic ratio (CTR), a simple radiographic measure, has prognostic value in hemodialysis, its role in PD is unclear because of limited evidence. We hypothesized that a high baseline CTR is independently associated with mortality in patients undergoing PD. Methods: We conducted a multicenter cohort study using data from the Fukuoka Peritoneal Dialysis Registry study. Of 1,217 patients who participated in the study between 2011 and 2020, 972 with a baseline CTR were included. The CTR was categorized into sex-specific quartiles. The primary and secondary outcomes were all-cause and cardiovascular mortality, respectively. We used multivariable Cox proportional hazards models to estimate hazard ratios (HRs) with 95% confidence intervals (CIs). Results: During a median follow-up of 731 days, 156 (16.0%) patients died, including 54 (5.6%) from cardiovascular causes. After multivariable adjustment, patients in the highest CTR quartile had significantly elevated risks of all-cause mortality (HR, 3.01; 95% CI: 1.85\u20135.04) and cardiovascular mortality (HR, 5.44; 95% CI: 2.17\u201313.59) compared with the lowest quartile. Each 1-standard deviation increase in the CTR was also associated with a higher risk of all-cause (HR, 1.40; 95% CI: 1.20\u20131.65) and cardiovascular mortality (HR, 1.68; 95% CI: 1.27\u20132.23). The findings were consistent in sensitivity analyses. Conclusion: An elevated baseline CTR is an independent predictor of all-cause and cardiovascular mortality in patients undergoing PD. This simple, readily available measure may be a useful tool for risk stratification in this high-risk population.<\/jats:p>","DOI":"10.1159\/000551506","type":"journal-article","created":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T16:00:35Z","timestamp":1777132835000},"page":"413-423","source":"Crossref","is-referenced-by-count":1,"title":["Associations between the Cardiothoracic Ratio and All-Cause and Cardiovascular Mortality in Patients Undergoing Peritoneal Dialysis: Fukuoka Peritoneal Dialysis Registry (F-PDR) 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